The genetically encoded tool set for investigating cAMP: more than the sum of its parts
Intracellular fluctuations of the second messenger cyclic AMP (cAMP) are regulated with spatial and temporal precision. This regulation is supported by the sophisticated arrangement of cyclases, phosphodiesterases, anchoring proteins and receptors for cAMP. Discovery of these nuances to cAMP signali...
Main Authors: | Neha ePatel, Matthew G Gold |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-08-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00164/full |
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