Consideration of Migraines Among Risk Factors for Postoperative Nausea and Vomiting
The impact of migraine on postoperative nausea and vomiting (PONV) is controversial, and few studies have focused on their relationship. Thus, we investigated the impact of migraine, among other risk factors, on PONV in a large retrospective study. We analyzed 10 years of clinical data from the Smar...
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MDPI AG
2020-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/10/3154 |
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| author | Jong-Ho Kim Man-sup Lim Sang-Hwa Lee Young-Suk Kwon Jae Jun Lee Jong-Hee Sohn |
| author_facet | Jong-Ho Kim Man-sup Lim Sang-Hwa Lee Young-Suk Kwon Jae Jun Lee Jong-Hee Sohn |
| author_sort | Jong-Ho Kim |
| collection | DOAJ |
| description | The impact of migraine on postoperative nausea and vomiting (PONV) is controversial, and few studies have focused on their relationship. Thus, we investigated the impact of migraine, among other risk factors, on PONV in a large retrospective study. We analyzed 10 years of clinical data from the Smart Clinical Data Warehouse of Hallym University Medical Center. PONV was defined as nausea or vomiting within the first 24 h after surgery. Patients diagnosed by a neurologist and with a history of triptan use before surgery were enrolled into the migraine group. We enrolled 208,029 patients aged > 18 years who underwent general anesthesia (GA), among whom 19,786 developed PONV within 24 h after GA and 1982 had migraine. Before propensity score matching, the unadjusted and fully adjusted odds ratios (ORs) for PONV in subjects with versus without migraine were 1.52 (95% confidence interval (CI), 1.34–1.72; <i>p</i> < 0.001) and 1.37 (95% CI, 1.21–1.56; <i>p</i> < 0.001), respectively. The OR for PONV in patients with migraine was also high (OR, 1.37; 95% CI, 1.13–1.66; <i>p</i> = 0.001) after matching. Our findings suggest that migraine is a significant risk factor for PONV. |
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| format | Article |
| id | doaj.art-7b9ebd2d10b344a78876164dbfc28b65 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T15:57:54Z |
| publishDate | 2020-09-01 |
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| spelling | doaj.art-7b9ebd2d10b344a78876164dbfc28b652023-11-20T15:31:21ZengMDPI AGJournal of Clinical Medicine2077-03832020-09-01910315410.3390/jcm9103154Consideration of Migraines Among Risk Factors for Postoperative Nausea and VomitingJong-Ho Kim0Man-sup Lim1Sang-Hwa Lee2Young-Suk Kwon3Jae Jun Lee4Jong-Hee Sohn5Department of Anesthesiology and Pain Medicine, Chuncheon Sacred Heart Hospital, Hallym University college of Medicine, Chuncheon 24253, KoreaDepartment of Medical Education, College of Medicine, Hallym University, Chuncheon 24253, KoreaDepartment of Neurology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24253, KoreaDepartment of Anesthesiology and Pain Medicine, Chuncheon Sacred Heart Hospital, Hallym University college of Medicine, Chuncheon 24253, KoreaDepartment of Anesthesiology and Pain Medicine, Chuncheon Sacred Heart Hospital, Hallym University college of Medicine, Chuncheon 24253, KoreaInstitute of New Frontier Research, College of Medicine, Hallym University, Chuncheon 24253, KoreaThe impact of migraine on postoperative nausea and vomiting (PONV) is controversial, and few studies have focused on their relationship. Thus, we investigated the impact of migraine, among other risk factors, on PONV in a large retrospective study. We analyzed 10 years of clinical data from the Smart Clinical Data Warehouse of Hallym University Medical Center. PONV was defined as nausea or vomiting within the first 24 h after surgery. Patients diagnosed by a neurologist and with a history of triptan use before surgery were enrolled into the migraine group. We enrolled 208,029 patients aged > 18 years who underwent general anesthesia (GA), among whom 19,786 developed PONV within 24 h after GA and 1982 had migraine. Before propensity score matching, the unadjusted and fully adjusted odds ratios (ORs) for PONV in subjects with versus without migraine were 1.52 (95% confidence interval (CI), 1.34–1.72; <i>p</i> < 0.001) and 1.37 (95% CI, 1.21–1.56; <i>p</i> < 0.001), respectively. The OR for PONV in patients with migraine was also high (OR, 1.37; 95% CI, 1.13–1.66; <i>p</i> = 0.001) after matching. Our findings suggest that migraine is a significant risk factor for PONV.https://www.mdpi.com/2077-0383/9/10/3154postoperative nausea and vomitingmigrainegeneral anesthesia |
| spellingShingle | Jong-Ho Kim Man-sup Lim Sang-Hwa Lee Young-Suk Kwon Jae Jun Lee Jong-Hee Sohn Consideration of Migraines Among Risk Factors for Postoperative Nausea and Vomiting Journal of Clinical Medicine postoperative nausea and vomiting migraine general anesthesia |
| title | Consideration of Migraines Among Risk Factors for Postoperative Nausea and Vomiting |
| title_full | Consideration of Migraines Among Risk Factors for Postoperative Nausea and Vomiting |
| title_fullStr | Consideration of Migraines Among Risk Factors for Postoperative Nausea and Vomiting |
| title_full_unstemmed | Consideration of Migraines Among Risk Factors for Postoperative Nausea and Vomiting |
| title_short | Consideration of Migraines Among Risk Factors for Postoperative Nausea and Vomiting |
| title_sort | consideration of migraines among risk factors for postoperative nausea and vomiting |
| topic | postoperative nausea and vomiting migraine general anesthesia |
| url | https://www.mdpi.com/2077-0383/9/10/3154 |
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