Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice
Torpor is a state of reduced metabolism and body temperature that conserves energy when food is scarce. Here the authors show that estrogen-sensitive neurons in the hypothalamus regulate torpor in mice, maintaining torpor in both sexes but initiating torpor and regulating core temperature differenti...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-20050-1 |
| _version_ | 1818721128857731072 |
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| author | Zhi Zhang Fernando M. C. V. Reis Yanlin He Jae W. Park Johnathon R. DiVittorio Nilla Sivakumar J. Edward van Veen Sandra Maesta-Pereira Michael Shum India Nichols Megan G. Massa Shawn Anderson Ketema Paul Marc Liesa Olujimi A. Ajijola Yong Xu Avishek Adhikari Stephanie M. Correa |
| author_facet | Zhi Zhang Fernando M. C. V. Reis Yanlin He Jae W. Park Johnathon R. DiVittorio Nilla Sivakumar J. Edward van Veen Sandra Maesta-Pereira Michael Shum India Nichols Megan G. Massa Shawn Anderson Ketema Paul Marc Liesa Olujimi A. Ajijola Yong Xu Avishek Adhikari Stephanie M. Correa |
| author_sort | Zhi Zhang |
| collection | DOAJ |
| description | Torpor is a state of reduced metabolism and body temperature that conserves energy when food is scarce. Here the authors show that estrogen-sensitive neurons in the hypothalamus regulate torpor in mice, maintaining torpor in both sexes but initiating torpor and regulating core temperature differentially across sex. |
| first_indexed | 2024-12-17T20:33:49Z |
| format | Article |
| id | doaj.art-7b9ecf04f1a846dda1413b72774ce3f8 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T20:33:49Z |
| publishDate | 2020-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-7b9ecf04f1a846dda1413b72774ce3f82022-12-21T21:33:30ZengNature PortfolioNature Communications2041-17232020-12-0111111410.1038/s41467-020-20050-1Estrogen-sensitive medial preoptic area neurons coordinate torpor in miceZhi Zhang0Fernando M. C. V. Reis1Yanlin He2Jae W. Park3Johnathon R. DiVittorio4Nilla Sivakumar5J. Edward van Veen6Sandra Maesta-Pereira7Michael Shum8India Nichols9Megan G. Massa10Shawn Anderson11Ketema Paul12Marc Liesa13Olujimi A. Ajijola14Yong Xu15Avishek Adhikari16Stephanie M. Correa17Department of Integrative Biology and Physiology, University of California Los AngelesDepartment of Psychology, University of California Los AngelesUSDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of MedicineDepartment of Integrative Biology and Physiology, University of California Los AngelesDepartment of Integrative Biology and Physiology, University of California Los AngelesDepartment of Integrative Biology and Physiology, University of California Los AngelesDepartment of Integrative Biology and Physiology, University of California Los AngelesDepartment of Psychology, University of California Los AngelesDivision of Endocrinology, Department of Medicine, David Geffen School of MedicineDepartment of Integrative Biology and Physiology, University of California Los AngelesDepartment of Integrative Biology and Physiology, University of California Los AngelesDepartment of Integrative Biology and Physiology, University of California Los AngelesDepartment of Integrative Biology and Physiology, University of California Los AngelesDivision of Endocrinology, Department of Medicine, David Geffen School of MedicineUCLA Cardiac Arrhythmia Center, Department of Medicine, David Geffen School of MedicineUSDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of MedicineBrain Research Institute, University of California Los AngelesDepartment of Integrative Biology and Physiology, University of California Los AngelesTorpor is a state of reduced metabolism and body temperature that conserves energy when food is scarce. Here the authors show that estrogen-sensitive neurons in the hypothalamus regulate torpor in mice, maintaining torpor in both sexes but initiating torpor and regulating core temperature differentially across sex.https://doi.org/10.1038/s41467-020-20050-1 |
| spellingShingle | Zhi Zhang Fernando M. C. V. Reis Yanlin He Jae W. Park Johnathon R. DiVittorio Nilla Sivakumar J. Edward van Veen Sandra Maesta-Pereira Michael Shum India Nichols Megan G. Massa Shawn Anderson Ketema Paul Marc Liesa Olujimi A. Ajijola Yong Xu Avishek Adhikari Stephanie M. Correa Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice Nature Communications |
| title | Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice |
| title_full | Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice |
| title_fullStr | Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice |
| title_full_unstemmed | Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice |
| title_short | Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice |
| title_sort | estrogen sensitive medial preoptic area neurons coordinate torpor in mice |
| url | https://doi.org/10.1038/s41467-020-20050-1 |
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