The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female Mice

The aim of this study is to investigate the contraceptive effect of the extract methanol of the leaves Hydrocotyle javanica Thumb and its effect threat of implantation, the quantity and condition of fetuses, histology appearance of the ovary and uterus and rate of pregnancy. The female mice were giv...

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Bibliographic Details
Main Authors: Rinidar R, M. Isa
Format: Article
Language:Indonesian
Published: Syiah Kuala University 2007-03-01
Series:Jurnal Kedokteran Hewan
Online Access:https://jurnal.usk.ac.id/JKH/article/view/3117
Description
Summary:The aim of this study is to investigate the contraceptive effect of the extract methanol of the leaves Hydrocotyle javanica Thumb and its effect threat of implantation, the quantity and condition of fetuses, histology appearance of the ovary and uterus and rate of pregnancy. The female mice were given orally either methanol extract of leaves, for 10 days in various doses: 20, 40, 60, and 80 gram/kg BW. On day 20, the mice were mated and when pregnancy occurred, treatment was stopped. On day 17 of pregnancy, the mice were sacrificed: uterus and ovaries were examined histologically. In conclusion, methanol extract of Hydrocotyle javanica Thumb shows contraceptive activity (P 0.05). Keywords: extract methanol, Hydrocotyle javanica Thumb, contraceptive
ISSN:1978-225X
2502-5600