The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female Mice

The aim of this study is to investigate the contraceptive effect of the extract methanol of the leaves Hydrocotyle javanica Thumb and its effect threat of implantation, the quantity and condition of fetuses, histology appearance of the ovary and uterus and rate of pregnancy. The female mice were giv...

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Main Authors: Rinidar R, M. Isa
Format: Article
Language:Indonesian
Published: Syiah Kuala University 2007-03-01
Series:Jurnal Kedokteran Hewan
Online Access:https://jurnal.usk.ac.id/JKH/article/view/3117
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author Rinidar R
M. Isa
author_facet Rinidar R
M. Isa
author_sort Rinidar R
collection DOAJ
description The aim of this study is to investigate the contraceptive effect of the extract methanol of the leaves Hydrocotyle javanica Thumb and its effect threat of implantation, the quantity and condition of fetuses, histology appearance of the ovary and uterus and rate of pregnancy. The female mice were given orally either methanol extract of leaves, for 10 days in various doses: 20, 40, 60, and 80 gram/kg BW. On day 20, the mice were mated and when pregnancy occurred, treatment was stopped. On day 17 of pregnancy, the mice were sacrificed: uterus and ovaries were examined histologically. In conclusion, methanol extract of Hydrocotyle javanica Thumb shows contraceptive activity (P 0.05). Keywords: extract methanol, Hydrocotyle javanica Thumb, contraceptive
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spelling doaj.art-7ba07738ec974cb4915035bebbe9ec862024-03-04T10:28:57ZindSyiah Kuala UniversityJurnal Kedokteran Hewan1978-225X2502-56002007-03-011110.21157/j.ked.hewan.v1i1.31172888The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female MiceRinidar R0M. Isa1Laboratorium Farmakologi Fakultas Kedokteran Hewan Universitas Syiah Kuala, Banda AcehLaboratorium Biokimia Fakultas Kedokteran Hewan Universitas Syiah Kuala, Banda AcehThe aim of this study is to investigate the contraceptive effect of the extract methanol of the leaves Hydrocotyle javanica Thumb and its effect threat of implantation, the quantity and condition of fetuses, histology appearance of the ovary and uterus and rate of pregnancy. The female mice were given orally either methanol extract of leaves, for 10 days in various doses: 20, 40, 60, and 80 gram/kg BW. On day 20, the mice were mated and when pregnancy occurred, treatment was stopped. On day 17 of pregnancy, the mice were sacrificed: uterus and ovaries were examined histologically. In conclusion, methanol extract of Hydrocotyle javanica Thumb shows contraceptive activity (P 0.05). Keywords: extract methanol, Hydrocotyle javanica Thumb, contraceptivehttps://jurnal.usk.ac.id/JKH/article/view/3117
spellingShingle Rinidar R
M. Isa
The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female Mice
Jurnal Kedokteran Hewan
title The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female Mice
title_full The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female Mice
title_fullStr The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female Mice
title_full_unstemmed The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female Mice
title_short The Contraceptive Effect of the Extract Methanol of The Leaves Hydrocotyle Javanica Thumb on Female Mice
title_sort contraceptive effect of the extract methanol of the leaves hydrocotyle javanica thumb on female mice
url https://jurnal.usk.ac.id/JKH/article/view/3117
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