Endometriosis and gynaecological cancers: molecular insights behind a complex machinery
Endometriosis is described as the presence of both endometrial glandular and stromal cells outside the uterine cavity. A major characterization of this disease is ectopic implantation of endometrial cells with increased migration. It is one of the leading causes of morbidity among premenopausal wome...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2021-12-01
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| Series: | Menopause Review |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Endometriosis-and-gynaecological-cancers-molecular-insights-behind-a-complex-machinery,4,45751,1,1.html |
| Summary: | Endometriosis is described as the presence of both endometrial glandular and stromal cells outside the uterine cavity. A major characterization of this disease is ectopic implantation of endometrial cells with increased migration. It is one of the leading causes of morbidity among premenopausal women, with a prevalence of 10–16% of women of reproductive age. Despite over century of intensive research, none of the current treatment options represents a real cure. Based on the current knowledge, endometriosis, particularly its atypical version, is considered to be a transitional form from benign disease to tumour. However, the exact mechanisms of this conversion are still not fully established. |
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| ISSN: | 1643-8876 2299-0038 |