O20 Pancreas transplant alone in patients with type 1 diabetes mellitus. Metabolic results after 5 years of experience
Introduction: Pancreas transplant alone (PTA) restores glycemic control with exogenous insulin independence in the after transplantation (posTx) in patients with type 1 diabetes mellitus (T1D). Between an 8% and 10% of the pancreas transplants cases are PTA. Advances in surgery techniques and immuno...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | Spanish |
| Published: |
Sello Editorial Lugones
2020-11-01
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| Series: | Revista de la Sociedad Argentina de Diabetes |
| Subjects: | |
| Online Access: | https://revistasad.com/index.php/diabetes/article/view/381 |
| _version_ | 1811319230446960640 |
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| author | Luis Grosembacher Roxana Groppa Javier Giunta Adriana Mabel Álvarez Lina Inés Capurro María Montserrat Castex Cintia Rodríguez Julia García Arabehety Patricia Liliana Duette Lucas Costa Sung Ho Hyon |
| author_facet | Luis Grosembacher Roxana Groppa Javier Giunta Adriana Mabel Álvarez Lina Inés Capurro María Montserrat Castex Cintia Rodríguez Julia García Arabehety Patricia Liliana Duette Lucas Costa Sung Ho Hyon |
| author_sort | Luis Grosembacher |
| collection | DOAJ |
| description | Introduction: Pancreas transplant alone (PTA) restores glycemic control with exogenous insulin independence in the after transplantation (posTx) in patients with type 1 diabetes mellitus (T1D). Between an 8% and 10% of the pancreas transplants cases are PTA. Advances in surgery techniques and immunosuppression improved the results of PTA. According to the International Registry on Organ Donation and Transplantation, survival increased to 5 years, to both the patient and the graft, 86% and 60%, respectively.
Objectives: Evaluate the metabolic PTA results in patients with T1D from the institutional Pancreatic Transplant Program.
Materials and Methods: Descriptive, observational study, in 5 T1D patients with PTA, made from 2015 to 2020; 3 were women, age 41±7 (range: 35 to 52 years old), diagnosed with T1D for 26±11 years. Pre-emptive transplant (preTx) insulin therapy, 4 with insulin infusion and 1 with MDI. PTA indication: 80% for diabetic retinopathy and metabolic lability, and 20% for psychological incapacity for insulin therapy. Donors’ age: 23.3±4.4 years, ischemic time: 10.8 hours. Pancreases were transplanted in the right iliac fossa, intraperitoneal, with anastomosis to iliac vessels. Quantitative variables with mean and standard deviation and qualitative variables with absolute frequencies are described. Correlation tendencies were calculated with Pearson’s correlation coefficient. |
| first_indexed | 2024-04-13T12:39:04Z |
| format | Article |
| id | doaj.art-7ba4c1de9b8a481f9e94995b3bd38791 |
| institution | Directory Open Access Journal |
| issn | 0325-5247 2346-9420 |
| language | Spanish |
| last_indexed | 2024-04-13T12:39:04Z |
| publishDate | 2020-11-01 |
| publisher | Sello Editorial Lugones |
| record_format | Article |
| series | Revista de la Sociedad Argentina de Diabetes |
| spelling | doaj.art-7ba4c1de9b8a481f9e94995b3bd387912022-12-22T02:46:34ZspaSello Editorial LugonesRevista de la Sociedad Argentina de Diabetes0325-52472346-94202020-11-01543Sup10510510.47196/diab.v54i3Sup.381313O20 Pancreas transplant alone in patients with type 1 diabetes mellitus. Metabolic results after 5 years of experienceLuis Grosembacher0Roxana Groppa1Javier Giunta2Adriana Mabel Álvarez3Lina Inés Capurro4María Montserrat Castex5Cintia Rodríguez6Julia García Arabehety7Patricia Liliana Duette8Lucas Costa9Sung Ho Hyon10HOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAHOSPITAL ITALIANO DE BUENOS AIRES, CIUDAD AUTÓNOMA DE BUENOS AIRES, ARGENTINAIntroduction: Pancreas transplant alone (PTA) restores glycemic control with exogenous insulin independence in the after transplantation (posTx) in patients with type 1 diabetes mellitus (T1D). Between an 8% and 10% of the pancreas transplants cases are PTA. Advances in surgery techniques and immunosuppression improved the results of PTA. According to the International Registry on Organ Donation and Transplantation, survival increased to 5 years, to both the patient and the graft, 86% and 60%, respectively. Objectives: Evaluate the metabolic PTA results in patients with T1D from the institutional Pancreatic Transplant Program. Materials and Methods: Descriptive, observational study, in 5 T1D patients with PTA, made from 2015 to 2020; 3 were women, age 41±7 (range: 35 to 52 years old), diagnosed with T1D for 26±11 years. Pre-emptive transplant (preTx) insulin therapy, 4 with insulin infusion and 1 with MDI. PTA indication: 80% for diabetic retinopathy and metabolic lability, and 20% for psychological incapacity for insulin therapy. Donors’ age: 23.3±4.4 years, ischemic time: 10.8 hours. Pancreases were transplanted in the right iliac fossa, intraperitoneal, with anastomosis to iliac vessels. Quantitative variables with mean and standard deviation and qualitative variables with absolute frequencies are described. Correlation tendencies were calculated with Pearson’s correlation coefficient.https://revistasad.com/index.php/diabetes/article/view/381trasplante de páncreasdiabetes tipo 1resultados metabólicos |
| spellingShingle | Luis Grosembacher Roxana Groppa Javier Giunta Adriana Mabel Álvarez Lina Inés Capurro María Montserrat Castex Cintia Rodríguez Julia García Arabehety Patricia Liliana Duette Lucas Costa Sung Ho Hyon O20 Pancreas transplant alone in patients with type 1 diabetes mellitus. Metabolic results after 5 years of experience Revista de la Sociedad Argentina de Diabetes trasplante de páncreas diabetes tipo 1 resultados metabólicos |
| title | O20 Pancreas transplant alone in patients with type 1 diabetes mellitus. Metabolic results after 5 years of experience |
| title_full | O20 Pancreas transplant alone in patients with type 1 diabetes mellitus. Metabolic results after 5 years of experience |
| title_fullStr | O20 Pancreas transplant alone in patients with type 1 diabetes mellitus. Metabolic results after 5 years of experience |
| title_full_unstemmed | O20 Pancreas transplant alone in patients with type 1 diabetes mellitus. Metabolic results after 5 years of experience |
| title_short | O20 Pancreas transplant alone in patients with type 1 diabetes mellitus. Metabolic results after 5 years of experience |
| title_sort | o20 pancreas transplant alone in patients with type 1 diabetes mellitus metabolic results after 5 years of experience |
| topic | trasplante de páncreas diabetes tipo 1 resultados metabólicos |
| url | https://revistasad.com/index.php/diabetes/article/view/381 |
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