A Pilot Feasibility Trial of an Upper Extremity Assistive System
Objective: To develop and clinically evaluate a customizable active upper extremity (UE) assistive system with integrated functional electrical stimulation (FES) that improves function and independence of individuals during activities of daily living (ADLs). Design: Single-arm, prospective, open-lab...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Archives of Rehabilitation Research and Clinical Translation |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590109523000708 |
| _version_ | 1827591547722399744 |
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| author | Emma Hammelef, BSE Saami J. Zakaria, MD Sarah H. Andersen, MA Thomas J. Kelly, IV, MA Namrata Grampurohit, PhD, OTR/L Mikael Avery, MArch, MS, OTR/L Alessandro Napoli, PhD Mary Jane Mulcahey, PhD, OTR/L Mijail Demian Serruya, MD, PhD |
| author_facet | Emma Hammelef, BSE Saami J. Zakaria, MD Sarah H. Andersen, MA Thomas J. Kelly, IV, MA Namrata Grampurohit, PhD, OTR/L Mikael Avery, MArch, MS, OTR/L Alessandro Napoli, PhD Mary Jane Mulcahey, PhD, OTR/L Mijail Demian Serruya, MD, PhD |
| author_sort | Emma Hammelef, BSE |
| collection | DOAJ |
| description | Objective: To develop and clinically evaluate a customizable active upper extremity (UE) assistive system with integrated functional electrical stimulation (FES) that improves function and independence of individuals during activities of daily living (ADLs). Design: Single-arm, prospective, open-label cohort feasibility trial. Setting: An academic research institution. Participants: Subjects were 5 adults with a medical history of stroke resulting in distal UE impairment (N=5). The subjects volunteered from recruitment materials that detailed information about the study. Interventions: A novel, wearable, lightweight, low-profile, and patient-tailored UE assistive system. It comprises a splint component and FES unit that may each be controlled by electromyography (EMG) signals, inertial measurement units (IMUs), manual control source (joystick), and/or voice control. Main Outcome Measure(s): Several occupational therapy outcome measures were used, including the Canadian Occupational Performance Measure (COPM), Action Research Arm Test (ARAT), The Box and Blocks Test (BBT), the ABILHAND-Manual Ability Measure, and Patient Reported Outcomes Measurement Information System (PROMIS) UE Short Form. Results: All participants learned to use our UE assistive system to perform ADLs and were able to use it independently at home. Most participants experienced a clinically meaningful improvement in both performance and satisfaction for the majority of their COPM goals while using the system. All participants experienced improvement in hand grip and release as shown by their baseline and post assessment scores for hand function (BBT, ARAT) and patient-reported outcomes (ABILHAND, PROMIS). Conclusions: The clinical outcomes suggest that our UE assistive system improves functional performance in patients with UE impairment, allowing them to engage more actively in ADLs. Further innovation including elbow and shoulder components will allow users to have more degrees of freedom during tasks. |
| first_indexed | 2024-03-09T01:34:17Z |
| format | Article |
| id | doaj.art-7ba82d7b075546d5ae7154f58aa843b8 |
| institution | Directory Open Access Journal |
| issn | 2590-1095 |
| language | English |
| last_indexed | 2024-03-09T01:34:17Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Archives of Rehabilitation Research and Clinical Translation |
| spelling | doaj.art-7ba82d7b075546d5ae7154f58aa843b82023-12-09T06:07:41ZengElsevierArchives of Rehabilitation Research and Clinical Translation2590-10952023-12-0154100308A Pilot Feasibility Trial of an Upper Extremity Assistive SystemEmma Hammelef, BSE0Saami J. Zakaria, MD1Sarah H. Andersen, MA2Thomas J. Kelly, IV, MA3Namrata Grampurohit, PhD, OTR/L4Mikael Avery, MArch, MS, OTR/L5Alessandro Napoli, PhD6Mary Jane Mulcahey, PhD, OTR/L7Mijail Demian Serruya, MD, PhD8Raphael Center for Neurorestoration, Farber Institute for Neuroscience, Thomas Jefferson University, 130 S 9th Street, Suite 2400, Philadelphia, PA 19107Raphael Center for Neurorestoration, Farber Institute for Neuroscience, Thomas Jefferson University, 130 S 9th Street, Suite 2400, Philadelphia, PA 19107Raphael Center for Neurorestoration, Farber Institute for Neuroscience, Thomas Jefferson University, 130 S 9th Street, Suite 2400, Philadelphia, PA 19107Raphael Center for Neurorestoration, Farber Institute for Neuroscience, Thomas Jefferson University, 130 S 9th Street, Suite 2400, Philadelphia, PA 19107Center for Outcomes and Measurement, College of Rehabilitation Sciences, Thomas Jefferson University, 901 Walnut Street, Suite 642, Philadelphia, PA 19107Raphael Center for Neurorestoration, Farber Institute for Neuroscience, Thomas Jefferson University, 130 S 9th Street, Suite 2400, Philadelphia, PA 19107; Studio Krea, Collingswood, NJRaphael Center for Neurorestoration, Farber Institute for Neuroscience, Thomas Jefferson University, 130 S 9th Street, Suite 2400, Philadelphia, PA 19107Center for Outcomes and Measurement, College of Rehabilitation Sciences, Thomas Jefferson University, 901 Walnut Street, Suite 642, Philadelphia, PA 19107Raphael Center for Neurorestoration, Farber Institute for Neuroscience, Thomas Jefferson University, 130 S 9th Street, Suite 2400, Philadelphia, PA 19107; Corresponding author Mijail Demian Serruya, 130 S 9th Street, Suite 2400, Philadelphia, PA 19107.Objective: To develop and clinically evaluate a customizable active upper extremity (UE) assistive system with integrated functional electrical stimulation (FES) that improves function and independence of individuals during activities of daily living (ADLs). Design: Single-arm, prospective, open-label cohort feasibility trial. Setting: An academic research institution. Participants: Subjects were 5 adults with a medical history of stroke resulting in distal UE impairment (N=5). The subjects volunteered from recruitment materials that detailed information about the study. Interventions: A novel, wearable, lightweight, low-profile, and patient-tailored UE assistive system. It comprises a splint component and FES unit that may each be controlled by electromyography (EMG) signals, inertial measurement units (IMUs), manual control source (joystick), and/or voice control. Main Outcome Measure(s): Several occupational therapy outcome measures were used, including the Canadian Occupational Performance Measure (COPM), Action Research Arm Test (ARAT), The Box and Blocks Test (BBT), the ABILHAND-Manual Ability Measure, and Patient Reported Outcomes Measurement Information System (PROMIS) UE Short Form. Results: All participants learned to use our UE assistive system to perform ADLs and were able to use it independently at home. Most participants experienced a clinically meaningful improvement in both performance and satisfaction for the majority of their COPM goals while using the system. All participants experienced improvement in hand grip and release as shown by their baseline and post assessment scores for hand function (BBT, ARAT) and patient-reported outcomes (ABILHAND, PROMIS). Conclusions: The clinical outcomes suggest that our UE assistive system improves functional performance in patients with UE impairment, allowing them to engage more actively in ADLs. Further innovation including elbow and shoulder components will allow users to have more degrees of freedom during tasks.http://www.sciencedirect.com/science/article/pii/S2590109523000708Activities of daily living (ADLs)HemiplegiaNeurological rehabilitationOccupational therapyRehabilitationStroke |
| spellingShingle | Emma Hammelef, BSE Saami J. Zakaria, MD Sarah H. Andersen, MA Thomas J. Kelly, IV, MA Namrata Grampurohit, PhD, OTR/L Mikael Avery, MArch, MS, OTR/L Alessandro Napoli, PhD Mary Jane Mulcahey, PhD, OTR/L Mijail Demian Serruya, MD, PhD A Pilot Feasibility Trial of an Upper Extremity Assistive System Archives of Rehabilitation Research and Clinical Translation Activities of daily living (ADLs) Hemiplegia Neurological rehabilitation Occupational therapy Rehabilitation Stroke |
| title | A Pilot Feasibility Trial of an Upper Extremity Assistive System |
| title_full | A Pilot Feasibility Trial of an Upper Extremity Assistive System |
| title_fullStr | A Pilot Feasibility Trial of an Upper Extremity Assistive System |
| title_full_unstemmed | A Pilot Feasibility Trial of an Upper Extremity Assistive System |
| title_short | A Pilot Feasibility Trial of an Upper Extremity Assistive System |
| title_sort | pilot feasibility trial of an upper extremity assistive system |
| topic | Activities of daily living (ADLs) Hemiplegia Neurological rehabilitation Occupational therapy Rehabilitation Stroke |
| url | http://www.sciencedirect.com/science/article/pii/S2590109523000708 |
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