Tissue factor (coagulation factor III): a potential double-edge molecule to be targeted and re-targeted toward cancer

Tissue factor (coagulation factor III): a potential double-edge molecule to be targeted and re-targeted toward cancer

Abstract Tissue factor (TF) is a protein that plays a critical role in blood clotting, but recent research has also shown its involvement in cancer development and progression. Herein, we provide an overview of the structure of TF and its involvement in signaling pathways that promote cancer cell pr...

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Bibliographic Details
Main Authors: Seyed Esmaeil Ahmadi, Ashkan Shabannezhad, Amir Kahrizi, Armin Akbar, Seyed Mehrab Safdari, Taraneh Hoseinnezhad, Mohammad Zahedi, Soroush Sadeghi, Mahsa Golizadeh Mojarrad, Majid Safa
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Biomarker Research
Subjects:
Tissue factor
Cancer
Metastasis
Angiogenesis
Targeted therapy
Re-Targeted therapy
Online Access:https://doi.org/10.1186/s40364-023-00504-6

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