Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities
Frangipani flower (Plumeria acuminata) and bitter grape (Tinospora crispa L. Miers) stem extract alone shows antimicrobial and antioxidant activities. However, there is a limited report about the actions from the combination of both extracts. Combinations of ethanol extract of white frangipani flowe...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Universitas Syiah Kuala, Faculty of Mathematics and Natural Science
2020-08-01
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| Series: | Jurnal Natural |
| Subjects: | |
| Online Access: | http://jurnal.unsyiah.ac.id/natural/article/view/17175 |
| _version_ | 1797230936459313152 |
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| author | KRISHNA PURNAWAN CANDRA WIJAYANTI KUSUMA WARDHANI ANTON RAHMADI MIFTAKHUR ROHMAH Rohmah YULIANI YULIANI |
| author_facet | KRISHNA PURNAWAN CANDRA WIJAYANTI KUSUMA WARDHANI ANTON RAHMADI MIFTAKHUR ROHMAH Rohmah YULIANI YULIANI |
| author_sort | KRISHNA PURNAWAN CANDRA |
| collection | DOAJ |
| description | Frangipani flower (Plumeria acuminata) and bitter grape (Tinospora crispa L. Miers) stem extract alone shows antimicrobial and antioxidant activities. However, there is a limited report about the actions from the combination of both extracts. Combinations of ethanol extract of white frangipani flower (EFF) and ethanol extract of the bitter grape stem (EBS), each of 0, 1, 2, and 3% were tested for inhibition against Staphylococcus aureus growth and DPPH (1,1-diphenyl,2-picrylhydrazyl) free radicals. A yield of 3.17 and 2.62 g of EFF and EBS, respectively, were resulted from 100 g of dried powdered of the white frangipani flower and bitter grape stem using 200 mL of absolute ethanol. The antimicrobial test was assayed using a 10% stock solution of extract diluted in water. The combination of EFF and EBS showed a synergistic effect on antimicrobial activity, but it proved an antagonistic effect on antioxidant activity. The combination of EFF 3% and EBS 3% showed the highest inhibition index on the S. aureus growth , i.e. 2.02±0.06, which is higher than the inhibition index of Amoxycillin 2%, i.e. 1.85±0.09. The highest antioxidant activity showed by 1% EFF alone (57.5 ± 0.60%), while the lowest was from the combination of EFF 1% and EBS 3% (23.4±0.30%). |
| first_indexed | 2024-04-24T15:36:24Z |
| format | Article |
| id | doaj.art-7baa1472b2404d52a9bf860554943bff |
| institution | Directory Open Access Journal |
| issn | 1411-8513 2541-4062 |
| language | English |
| last_indexed | 2024-04-24T15:36:24Z |
| publishDate | 2020-08-01 |
| publisher | Universitas Syiah Kuala, Faculty of Mathematics and Natural Science |
| record_format | Article |
| series | Jurnal Natural |
| spelling | doaj.art-7baa1472b2404d52a9bf860554943bff2024-04-02T01:54:12ZengUniversitas Syiah Kuala, Faculty of Mathematics and Natural ScienceJurnal Natural1411-85132541-40622020-08-01203747910.24815/jn.v20i3.1717511507Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activitiesKRISHNA PURNAWAN CANDRA0WIJAYANTI KUSUMA WARDHANI1ANTON RAHMADI2MIFTAKHUR ROHMAH Rohmah3YULIANI YULIANI4Mulawarman UniversityMulawarman UniversityMulawarman UniversityMulawarman UniversityMulawarman UniversityFrangipani flower (Plumeria acuminata) and bitter grape (Tinospora crispa L. Miers) stem extract alone shows antimicrobial and antioxidant activities. However, there is a limited report about the actions from the combination of both extracts. Combinations of ethanol extract of white frangipani flower (EFF) and ethanol extract of the bitter grape stem (EBS), each of 0, 1, 2, and 3% were tested for inhibition against Staphylococcus aureus growth and DPPH (1,1-diphenyl,2-picrylhydrazyl) free radicals. A yield of 3.17 and 2.62 g of EFF and EBS, respectively, were resulted from 100 g of dried powdered of the white frangipani flower and bitter grape stem using 200 mL of absolute ethanol. The antimicrobial test was assayed using a 10% stock solution of extract diluted in water. The combination of EFF and EBS showed a synergistic effect on antimicrobial activity, but it proved an antagonistic effect on antioxidant activity. The combination of EFF 3% and EBS 3% showed the highest inhibition index on the S. aureus growth , i.e. 2.02±0.06, which is higher than the inhibition index of Amoxycillin 2%, i.e. 1.85±0.09. The highest antioxidant activity showed by 1% EFF alone (57.5 ± 0.60%), while the lowest was from the combination of EFF 1% and EBS 3% (23.4±0.30%).http://jurnal.unsyiah.ac.id/natural/article/view/17175plumeria, bitter grape, tinospora, staphylococcus aureus |
| spellingShingle | KRISHNA PURNAWAN CANDRA WIJAYANTI KUSUMA WARDHANI ANTON RAHMADI MIFTAKHUR ROHMAH Rohmah YULIANI YULIANI Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities Jurnal Natural plumeria, bitter grape, tinospora, staphylococcus aureus |
| title | Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities |
| title_full | Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities |
| title_fullStr | Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities |
| title_full_unstemmed | Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities |
| title_short | Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities |
| title_sort | study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities |
| topic | plumeria, bitter grape, tinospora, staphylococcus aureus |
| url | http://jurnal.unsyiah.ac.id/natural/article/view/17175 |
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