Chronic high-fat diet impairs collecting lymphatic vessel function in mice.

Chronic high-fat diet impairs collecting lymphatic vessel function in mice.

Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction. However, the effects of obesity on lymphatic function have...

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Bibliographic Details
Main Authors: Katrin S Blum, Sinem Karaman, Steven T Proulx, Alexandra M Ochsenbein, Paola Luciani, Jean-Christophe Leroux, Christian Wolfrum, Michael Detmar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979858?pdf=render

Internet

http://europepmc.org/articles/PMC3979858?pdf=render

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