Looking for a Treatment for the Early Stage of Alzheimer’s Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin

Looking for a Treatment for the Early Stage of Alzheimer’s Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin

Background: At the earliest stage of Alzheimer’s disease (AD), although patients are still asymptomatic, cerebral alterations have already been triggered. In addition to beta amyloid (Aβ) accumulation, both glial alterations and neuroinflammation have been documented at this stage. Starting treatmen...

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Bibliographic Details
Main Authors: Roberta Facchinetti, Marta Valenza, Maria Rosanna Bronzuoli, Giorgia Menegoni, Patrizia Ratano, Luca Steardo, Patrizia Campolongo, Caterina Scuderi
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
astrocytes
beta amyloid
luteolin
microglia
neuroinflammation
neuroprotection
Online Access:https://www.mdpi.com/1422-0067/21/11/3802

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