Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation

Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation

ObjectiveSerum neurofilament light chain (sNfL) is increasingly used as a neuroaxonal injury biomarker in the elderly. Besides age, little is known about how other physiological factors like renal function and body mass index (BMI) alter its levels. Here, we investigated the association of estimated...

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Bibliographic Details
Main Authors: Alexandros A. Polymeris, Fabrice Helfenstein, Pascal Benkert, Stefanie Aeschbacher, David Leppert, Michael Coslovsky, Eline Willemse, Sabine Schaedelin, Manuel R. Blum, Nicolas Rodondi, Tobias Reichlin, Giorgio Moschovitis, Jens Wuerfel, Gian Marco De Marchis, Stefan T. Engelter, Philippe A. Lyrer, David Conen, Michael Kühne, Stefan Osswald, Leo H. Bonati, Jens Kuhle, the Swiss-AF Investigators
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Neuroscience
Subjects:
neurofilament light
renal function
glomerular filtration rate
body mass index
elderly
atrial fibrillation
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.819010/full

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