A case of sine scleroderma with parenchymal lung disease

Systemic sclerosis sine scleroderma is a subtype of scleroderma, which is characterized by involvement of visceral organs, but no characteristic skin alteration. The involved organs could be kidneys, heart, gastrointestinal system, and lungs. Interstitial lung disease (ILD) is one of the pulmonary m...

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Main Authors: Mansoor Karimifar, Hourosadat Hashemi, Mozhgan Karimifar, Amir Kazizadeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Advanced Biomedical Research
Subjects:
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=39;epage=39;aulast=Karimifar
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author Mansoor Karimifar
Hourosadat Hashemi
Mozhgan Karimifar
Amir Kazizadeh
author_facet Mansoor Karimifar
Hourosadat Hashemi
Mozhgan Karimifar
Amir Kazizadeh
author_sort Mansoor Karimifar
collection DOAJ
description Systemic sclerosis sine scleroderma is a subtype of scleroderma, which is characterized by involvement of visceral organs, but no characteristic skin alteration. The involved organs could be kidneys, heart, gastrointestinal system, and lungs. Interstitial lung disease (ILD) is one of the pulmonary manifestations of sine scleroderma. We report a 38-year-old woman presenting with chill, fever, generalized malaise, dyspnea on exertion, and dry cough with a history of Raynaud′s phenomenon, who was evaluated by physical examination, spirometry, and computed tomography scan, that all lead to the diagnosis of ILD. Combination of high-titer positive anti-nuclear antibody, high erythrocyte sedimentation rate, positive C-reactive protein, and ILD could be explained by sine scleroderma.
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spelling doaj.art-7bb0a88c5e4b48dc907533aeb51d9bf22022-12-22T01:15:21ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752277-91752014-01-0131393910.4103/2277-9175.125728A case of sine scleroderma with parenchymal lung diseaseMansoor KarimifarHourosadat HashemiMozhgan KarimifarAmir KazizadehSystemic sclerosis sine scleroderma is a subtype of scleroderma, which is characterized by involvement of visceral organs, but no characteristic skin alteration. The involved organs could be kidneys, heart, gastrointestinal system, and lungs. Interstitial lung disease (ILD) is one of the pulmonary manifestations of sine scleroderma. We report a 38-year-old woman presenting with chill, fever, generalized malaise, dyspnea on exertion, and dry cough with a history of Raynaud′s phenomenon, who was evaluated by physical examination, spirometry, and computed tomography scan, that all lead to the diagnosis of ILD. Combination of high-titer positive anti-nuclear antibody, high erythrocyte sedimentation rate, positive C-reactive protein, and ILD could be explained by sine scleroderma.http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=39;epage=39;aulast=KarimifarInterstitial lung diseasesystemic sclerosis sine sclerodermarituximab
spellingShingle Mansoor Karimifar
Hourosadat Hashemi
Mozhgan Karimifar
Amir Kazizadeh
A case of sine scleroderma with parenchymal lung disease
Advanced Biomedical Research
Interstitial lung disease
systemic sclerosis sine scleroderma
rituximab
title A case of sine scleroderma with parenchymal lung disease
title_full A case of sine scleroderma with parenchymal lung disease
title_fullStr A case of sine scleroderma with parenchymal lung disease
title_full_unstemmed A case of sine scleroderma with parenchymal lung disease
title_short A case of sine scleroderma with parenchymal lung disease
title_sort case of sine scleroderma with parenchymal lung disease
topic Interstitial lung disease
systemic sclerosis sine scleroderma
rituximab
url http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=39;epage=39;aulast=Karimifar
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