Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome

Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome

Abstract Objective Numerous studies have confirmed the correlation of microRNAs (miRNAs) with human disease, yet few have explored the role of miR-135 in preeclampsia (PE). This study intends to discuss miR-135’s function in inflammatory response in PE by modulating proprotein convertase subtilisin/...

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Bibliographic Details
Main Authors: Xiaolan Zhao, Xun Zhang, Zhao Wu, Jie Mei, Lingling Li, Yujue Wang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Medicine
Subjects:
Preeclampsia
MicroRNA-135
PCSK6
NLR pyrin domain containing 3
Online Access:https://doi.org/10.1186/s10020-021-00335-x

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