Value of Brain Natriuretic Peptide in Predicting Prognosis of Coronary Artery Disease in Myocardial Infarction
Background: Brain natriuretic peptide (BNP) is an important predictor of outcomes in patients with heart failure but the prognostic value of BNP elevation in patients with myocardial infarction is not MI in completely defined. This study aims to identify the prognostic value of BNP in patients with...
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| Format: | Article |
| Language: | English |
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Shahid Beheshti University of Medical Sciences
2020-12-01
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| Series: | Novelty in Biomedicine |
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| Online Access: | https://journals.sbmu.ac.ir/nbm/article/view/32128 |
| _version_ | 1818647903750586368 |
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| author | Roxana Sadeghi Roja Qobadighadikolaei Maryam Ekhlaspour Mohammad Sistanizad |
| author_facet | Roxana Sadeghi Roja Qobadighadikolaei Maryam Ekhlaspour Mohammad Sistanizad |
| author_sort | Roxana Sadeghi |
| collection | DOAJ |
| description | Background: Brain natriuretic peptide (BNP) is an important predictor of outcomes in patients with heart failure but the prognostic value of BNP elevation in patients with myocardial infarction is not MI in completely defined. This study aims to identify the prognostic value of BNP in patients with MI.
Materials and Methods: We studied patients with MI who were hospitalized in the Coronary Care Unit of Imam Hossein Hospital. Patients' demographic data, past medical and drug history besides echocardiography report and BNP levels were documented during the hospital stay and echocardiography was repeated after 3 months.
Results: This prospective observational cross-section study was done between January 2018 through January 2019. During the study period, 124 patients were recruited. There was significant negative correlation between BNP levels and ejection fraction (P=0.001), systolic blood pressure (P=0.012), diastolic blood pressure (P=0.003) and ratio between early mitral inflow velocity and early diastolic mitral annular velocity (E/e') (P=0.03) and EF in follow up (P=0.001). The correlation between BNP levels with infarction location (P=0.40), arterial involvement in the left main coronary artery (P=0.15), left anterior descending artery (P=0.53), left circumflex artery (P= 0.97), right coronary artery (P=0.50) and hospital stay (P=0.66) were not significant.
Conclusion: BNP is a valuable marker for predicting prognosis in patients with the acute coronary syndrome. Also, it could be considered as a prognostic long-term marker for predicting the EF of patients with AMI. |
| first_indexed | 2024-12-17T01:09:56Z |
| format | Article |
| id | doaj.art-7bb640e679044772baf7de1242af9c7d |
| institution | Directory Open Access Journal |
| issn | 2345-3907 |
| language | English |
| last_indexed | 2024-12-17T01:09:56Z |
| publishDate | 2020-12-01 |
| publisher | Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | Novelty in Biomedicine |
| spelling | doaj.art-7bb640e679044772baf7de1242af9c7d2022-12-21T22:09:10ZengShahid Beheshti University of Medical SciencesNovelty in Biomedicine2345-39072020-12-0192657010.22037/nbm.vi.3212832128Value of Brain Natriuretic Peptide in Predicting Prognosis of Coronary Artery Disease in Myocardial InfarctionRoxana SadeghiRoja QobadighadikolaeiMaryam EkhlaspourMohammad SistanizadBackground: Brain natriuretic peptide (BNP) is an important predictor of outcomes in patients with heart failure but the prognostic value of BNP elevation in patients with myocardial infarction is not MI in completely defined. This study aims to identify the prognostic value of BNP in patients with MI. Materials and Methods: We studied patients with MI who were hospitalized in the Coronary Care Unit of Imam Hossein Hospital. Patients' demographic data, past medical and drug history besides echocardiography report and BNP levels were documented during the hospital stay and echocardiography was repeated after 3 months. Results: This prospective observational cross-section study was done between January 2018 through January 2019. During the study period, 124 patients were recruited. There was significant negative correlation between BNP levels and ejection fraction (P=0.001), systolic blood pressure (P=0.012), diastolic blood pressure (P=0.003) and ratio between early mitral inflow velocity and early diastolic mitral annular velocity (E/e') (P=0.03) and EF in follow up (P=0.001). The correlation between BNP levels with infarction location (P=0.40), arterial involvement in the left main coronary artery (P=0.15), left anterior descending artery (P=0.53), left circumflex artery (P= 0.97), right coronary artery (P=0.50) and hospital stay (P=0.66) were not significant. Conclusion: BNP is a valuable marker for predicting prognosis in patients with the acute coronary syndrome. Also, it could be considered as a prognostic long-term marker for predicting the EF of patients with AMI.https://journals.sbmu.ac.ir/nbm/article/view/32128brain natriuretic peptide, myocardial infarction, prognosis |
| spellingShingle | Roxana Sadeghi Roja Qobadighadikolaei Maryam Ekhlaspour Mohammad Sistanizad Value of Brain Natriuretic Peptide in Predicting Prognosis of Coronary Artery Disease in Myocardial Infarction Novelty in Biomedicine brain natriuretic peptide, myocardial infarction, prognosis |
| title | Value of Brain Natriuretic Peptide in Predicting Prognosis of Coronary Artery Disease in Myocardial Infarction |
| title_full | Value of Brain Natriuretic Peptide in Predicting Prognosis of Coronary Artery Disease in Myocardial Infarction |
| title_fullStr | Value of Brain Natriuretic Peptide in Predicting Prognosis of Coronary Artery Disease in Myocardial Infarction |
| title_full_unstemmed | Value of Brain Natriuretic Peptide in Predicting Prognosis of Coronary Artery Disease in Myocardial Infarction |
| title_short | Value of Brain Natriuretic Peptide in Predicting Prognosis of Coronary Artery Disease in Myocardial Infarction |
| title_sort | value of brain natriuretic peptide in predicting prognosis of coronary artery disease in myocardial infarction |
| topic | brain natriuretic peptide, myocardial infarction, prognosis |
| url | https://journals.sbmu.ac.ir/nbm/article/view/32128 |
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