Chiral Analysis of Pesticides and Emerging Contaminants by Capillary Electrophoresis—Application to Toxicity Evaluation
Chiral analysis is a very relevant topic in environmental chemistry. This is due to the different properties of the stereoisomers of chiral compounds. In the case of agrochemicals, the desired activity, degradation rate, or toxicity, among other characteristics, may differ between stereoisomers, and...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Toxics |
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| Online Access: | https://www.mdpi.com/2305-6304/12/3/185 |
| _version_ | 1797239173038473216 |
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| author | Laura García-Cansino María Luisa Marina María Ángeles García |
| author_facet | Laura García-Cansino María Luisa Marina María Ángeles García |
| author_sort | Laura García-Cansino |
| collection | DOAJ |
| description | Chiral analysis is a very relevant topic in environmental chemistry. This is due to the different properties of the stereoisomers of chiral compounds. In the case of agrochemicals, the desired activity, degradation rate, or toxicity, among other characteristics, may differ between stereoisomers, and the same is true for emerging contaminants, such as pharmaceuticals and cosmetics. Therefore, the development of chiral analytical methodologies enabling their determination in samples of environmental interest is paramount. Although other techniques have been widely employed to carry out chiral separations, such as HPLC, GC, and SFC, capillary electrophoresis (CE) has attracted a lot of attention in the field of chiral analysis due to its simplicity, flexibility, and low cost. In fact, chromatographic columns are not needed, and the consumption of reagents and samples is very low due to the small dimensions of the separation capillaries. This article reviews the characteristics of the chiral methodologies developed by CE for the stereoselective analysis of pesticides and emerging contaminants in environmental samples (water and soil), as well as pesticides in food samples and commercial agrochemical formulations. Applications of the developed CE methodologies in stability and toxicity studies of these chiral contaminants are also reviewed. |
| first_indexed | 2024-04-24T17:47:19Z |
| format | Article |
| id | doaj.art-7bb7651f0c244a86a69c96c030713ab2 |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-04-24T17:47:19Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-7bb7651f0c244a86a69c96c030713ab22024-03-27T14:06:11ZengMDPI AGToxics2305-63042024-02-0112318510.3390/toxics12030185Chiral Analysis of Pesticides and Emerging Contaminants by Capillary Electrophoresis—Application to Toxicity EvaluationLaura García-Cansino0María Luisa Marina1María Ángeles García2Universidad de Alcalá, Departamento de Química Analítica, Química Física e Ingeniería Química, Ctra. Madrid-Barcelona Km. 33.600, 28871 Alcalá de Henares, Madrid, SpainUniversidad de Alcalá, Departamento de Química Analítica, Química Física e Ingeniería Química, Ctra. Madrid-Barcelona Km. 33.600, 28871 Alcalá de Henares, Madrid, SpainUniversidad de Alcalá, Departamento de Química Analítica, Química Física e Ingeniería Química, Ctra. Madrid-Barcelona Km. 33.600, 28871 Alcalá de Henares, Madrid, SpainChiral analysis is a very relevant topic in environmental chemistry. This is due to the different properties of the stereoisomers of chiral compounds. In the case of agrochemicals, the desired activity, degradation rate, or toxicity, among other characteristics, may differ between stereoisomers, and the same is true for emerging contaminants, such as pharmaceuticals and cosmetics. Therefore, the development of chiral analytical methodologies enabling their determination in samples of environmental interest is paramount. Although other techniques have been widely employed to carry out chiral separations, such as HPLC, GC, and SFC, capillary electrophoresis (CE) has attracted a lot of attention in the field of chiral analysis due to its simplicity, flexibility, and low cost. In fact, chromatographic columns are not needed, and the consumption of reagents and samples is very low due to the small dimensions of the separation capillaries. This article reviews the characteristics of the chiral methodologies developed by CE for the stereoselective analysis of pesticides and emerging contaminants in environmental samples (water and soil), as well as pesticides in food samples and commercial agrochemical formulations. Applications of the developed CE methodologies in stability and toxicity studies of these chiral contaminants are also reviewed.https://www.mdpi.com/2305-6304/12/3/185agrochemical formulationscapillary electrophoresischiral analysisemerging contaminantsenvironmentally friendly analytical methodologiesfood |
| spellingShingle | Laura García-Cansino María Luisa Marina María Ángeles García Chiral Analysis of Pesticides and Emerging Contaminants by Capillary Electrophoresis—Application to Toxicity Evaluation Toxics agrochemical formulations capillary electrophoresis chiral analysis emerging contaminants environmentally friendly analytical methodologies food |
| title | Chiral Analysis of Pesticides and Emerging Contaminants by Capillary Electrophoresis—Application to Toxicity Evaluation |
| title_full | Chiral Analysis of Pesticides and Emerging Contaminants by Capillary Electrophoresis—Application to Toxicity Evaluation |
| title_fullStr | Chiral Analysis of Pesticides and Emerging Contaminants by Capillary Electrophoresis—Application to Toxicity Evaluation |
| title_full_unstemmed | Chiral Analysis of Pesticides and Emerging Contaminants by Capillary Electrophoresis—Application to Toxicity Evaluation |
| title_short | Chiral Analysis of Pesticides and Emerging Contaminants by Capillary Electrophoresis—Application to Toxicity Evaluation |
| title_sort | chiral analysis of pesticides and emerging contaminants by capillary electrophoresis application to toxicity evaluation |
| topic | agrochemical formulations capillary electrophoresis chiral analysis emerging contaminants environmentally friendly analytical methodologies food |
| url | https://www.mdpi.com/2305-6304/12/3/185 |
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