Stigmast-4-en-6β-ol-3-one decreases viability and induces apoptosis and ferroptosis in liver cancer cells by reducing E2F1

Stigmast-4-en-6β-ol-3-one decreases viability and induces apoptosis and ferroptosis in liver cancer cells by reducing E2F1

ABSTRACTHepatocellular carcinoma (HCC) is a frequently occurring malignant gastrointestinal cancer. The 5-year survival rate of HCC is still below 8%, and thus, identifying more effective therapeutic methods is needed. Here, we evaluated the effects of Stigmast-4-en-6β-ol-3-one (S463) on the viabili...

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Bibliographic Details
Main Authors: Zhiyun Zhang, Jian Wang, Weiping Wan, Zhengchao Shen, Aixue Zuo, Rong Chen, Qinyi Wu, Enli Cai, Feng Huang, Rongping Zhang, Xinan Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Animal Cells and Systems
Subjects:
Stigmast-4-en-6β-ol-3-one
liver cancer
apoptosis
ferroptosis
E2F1
Online Access:https://www.tandfonline.com/doi/10.1080/19768354.2023.2282224

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