Oronasal or Intramuscular Immunization with a Thermo-Attenuated ASFV Strain Provides Full Clinical Protection against Georgia 2007/1 Challenge

Oronasal or Intramuscular Immunization with a Thermo-Attenuated ASFV Strain Provides Full Clinical Protection against Georgia 2007/1 Challenge

African swine fever (ASF) is a contagious viral disease of suids that induces high mortality in domestic pigs and wild boars. Given the current spread of ASF, the development of a vaccine is a priority. During an attempt to inactivate the Georgia 2007/1 strain via heat treatment, we fortuitously gen...

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Bibliographic Details
Main Authors: Olivier Bourry, Evelyne Hutet, Mireille Le Dimna, Pierrick Lucas, Yannick Blanchard, Amélie Chastagner, Frédéric Paboeuf, Marie-Frédérique Le Potier
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Viruses
Subjects:
ASF
live attenuated vaccine
oronasal
intramuscular
Online Access:https://www.mdpi.com/1999-4915/14/12/2777

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