Comparative Analysis of T-Cell Responses to Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein in Inflammatory Demyelinating Central Nervous System Diseases

Comparative Analysis of T-Cell Responses to Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein in Inflammatory Demyelinating Central Nervous System Diseases

Autoantibodies against aquaporin-4 (AQP4-Ab) and myelin oligodendrocyte glycoprotein (MOG-Ab) are associated with rare central nervous system inflammatory demyelinating diseases like neuromyelitis optica spectrum disorders (NMOSD). Previous studies have shown that not only antibodies, but also autor...

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Bibliographic Details
Main Authors: Livia Sophie Hofer, Melanie Ramberger, Viktoria Gredler, Anna Sophie Pescoller, Kevin Rostásy, Mireia Sospedra, Harald Hegen, Thomas Berger, Andreas Lutterotti, Markus Reindl
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
neuromyelitis optica spectrum disorder
aquaporin-4
myelin oligodendrocyte glycoprotein
antibody
T-cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01188/full

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