Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells

Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells

Summary: Renal cell carcinoma (RCC) is a deadly malignancy due to its tendency to metastasize and resistance to chemotherapy. Stem-like tumor cells often confer these aggressive behaviors. We discovered an endoglin (CD105)-expressing subpopulation in human RCC xenografts and patient samples with a g...

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Bibliographic Details
Main Authors: Junhui Hu, Wei Guan, Peijun Liu, Jin Dai, Kun Tang, Haibing Xiao, Yuan Qian, Allison C. Sharrow, Zhangqun Ye, Lily Wu, Hua Xu
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117303193

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