Effect of Two Lipoprotein (a)-Associated Genetic Variants on Plasminogen Levels and Fibrinolysis

Effect of Two Lipoprotein (a)-Associated Genetic Variants on Plasminogen Levels and Fibrinolysis

Two genetic variants (rs3798220 and rs10455872) in the apolipoprotein (a) gene (LPA) have been implicated in cardiovascular disease (CVD), presumably through their association with lipoprotein (a) [Lp(a)] levels. While Lp(a) is recognized as a lipoprotein with atherogenic and thrombogenic characteri...

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Bibliographic Details
Main Authors: Hong Wang, Chan E. Hong, Joshua P. Lewis, Yanbei Zhu, Xing Wang, Xin Chu, Joshua Backman, Ziying Hu, Peixin Yang, Christopher D. Still, Glenn S. Gerhard, Mao Fu
Format: Article
Language:English
Published: Oxford University Press 2016-11-01
Series:G3: Genes, Genomes, Genetics
Subjects:
lipoprotein (a)
plasminogen
fibrinolysis
genetics
thrombogenicity
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.034702

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