Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial.

Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial.

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and carries a dismal prognosis. We have developed a conditional cytotoxic/immunotherapeutic approach using adenoviral vectors (Ads) encoding the immunostimulatory cytokine, human soluble fms-like tyrosine kinase 3 ligand...

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Bibliographic Details
Main Authors: Weidong Xiong, Marianela Candolfi, Chunyan Liu, A K M Ghulam Muhammad, Kader Yagiz, Mariana Puntel, Peter F Moore, Julie Avalos, John D Young, Dorothy Khan, Randy Donelson, G Elizabeth Pluhar, John R Ohlfest, Kolja Wawrowsky, Pedro R Lowenstein, Maria G Castro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2884015?pdf=render

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