Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane

Glucosinolates are a kind of important sulfur-containing anionic hydrophilic natural products in cruciferous vegetables. Under the catalysis of endogenous myrosinase, glucosinolates can be hydrolyzed to produce active substances with anti-cancer, anti-oxidation, antimicrobial and other effects, whic...

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Main Authors: Xuan ZHANG, Mingshuo TIAN, Jian WANG, Mingkun GAO, Yuhang GAO, Yuan LIU, Donghui XU, Guangyang LIU
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2022-09-01
Series:Shipin gongye ke-ji
Subjects:
Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021040167
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author Xuan ZHANG
Mingshuo TIAN
Jian WANG
Mingkun GAO
Yuhang GAO
Yuan LIU
Donghui XU
Guangyang LIU
author_facet Xuan ZHANG
Mingshuo TIAN
Jian WANG
Mingkun GAO
Yuhang GAO
Yuan LIU
Donghui XU
Guangyang LIU
author_sort Xuan ZHANG
collection DOAJ
description Glucosinolates are a kind of important sulfur-containing anionic hydrophilic natural products in cruciferous vegetables. Under the catalysis of endogenous myrosinase, glucosinolates can be hydrolyzed to produce active substances with anti-cancer, anti-oxidation, antimicrobial and other effects, which have attracted wide attention of researchers. Sulforaphane is a thioglucose monomer with the best anticancer effect and the strongest efficacy. As an effective component of drugs or functional foods, it has high research value and broad application prospects. In this study, the source, structure, properties, functional activities of sulforaphane are summarized, and its extraction technology, separation and purification methods and anticancer applications are systematically introduced. The research prospect is discussed and anticipated, in order to provide research basis and technical support for the research and development of sulforaphane functional components and high value-added utilization.
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spelling doaj.art-7bc225421f2141689ff50a87548d46dd2022-12-22T03:39:39ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062022-09-01431742443410.13386/j.issn1002-0306.20210401672021040167-17Research Progress in Extraction, Purification and Anticancer Function of SulforaphaneXuan ZHANG0Mingshuo TIAN1Jian WANG2Mingkun GAO3Yuhang GAO4Yuan LIU5Donghui XU6Guangyang LIU7College of Agriculture and Forestry Science and Technology, Hebei North University, Hebei Key Laboratory of Quality & Safety Analysis-Testing for Agro-Products and Food, Zhangjiakou 075000, ChinaCollege of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, ChinaCollege of Agriculture and Forestry Science and Technology, Hebei North University, Hebei Key Laboratory of Quality & Safety Analysis-Testing for Agro-Products and Food, Zhangjiakou 075000, ChinaThe Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Laboratory of Quality & Safety Risk Assessment for Vegetable Products (Beijing), Ministry of Agriculture and Rural Affairs of China, Beijing 100081, ChinaThe Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Laboratory of Quality & Safety Risk Assessment for Vegetable Products (Beijing), Ministry of Agriculture and Rural Affairs of China, Beijing 100081, ChinaCollege of Agriculture and Forestry Science and Technology, Hebei North University, Hebei Key Laboratory of Quality & Safety Analysis-Testing for Agro-Products and Food, Zhangjiakou 075000, ChinaThe Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Laboratory of Quality & Safety Risk Assessment for Vegetable Products (Beijing), Ministry of Agriculture and Rural Affairs of China, Beijing 100081, ChinaThe Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Laboratory of Quality & Safety Risk Assessment for Vegetable Products (Beijing), Ministry of Agriculture and Rural Affairs of China, Beijing 100081, ChinaGlucosinolates are a kind of important sulfur-containing anionic hydrophilic natural products in cruciferous vegetables. Under the catalysis of endogenous myrosinase, glucosinolates can be hydrolyzed to produce active substances with anti-cancer, anti-oxidation, antimicrobial and other effects, which have attracted wide attention of researchers. Sulforaphane is a thioglucose monomer with the best anticancer effect and the strongest efficacy. As an effective component of drugs or functional foods, it has high research value and broad application prospects. In this study, the source, structure, properties, functional activities of sulforaphane are summarized, and its extraction technology, separation and purification methods and anticancer applications are systematically introduced. The research prospect is discussed and anticipated, in order to provide research basis and technical support for the research and development of sulforaphane functional components and high value-added utilization.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021040167sulforaphanestructural propertiesextraction methodseparation and purificationanticancer application
spellingShingle Xuan ZHANG
Mingshuo TIAN
Jian WANG
Mingkun GAO
Yuhang GAO
Yuan LIU
Donghui XU
Guangyang LIU
Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane
Shipin gongye ke-ji
sulforaphane
structural properties
extraction method
separation and purification
anticancer application
title Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane
title_full Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane
title_fullStr Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane
title_full_unstemmed Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane
title_short Research Progress in Extraction, Purification and Anticancer Function of Sulforaphane
title_sort research progress in extraction purification and anticancer function of sulforaphane
topic sulforaphane
structural properties
extraction method
separation and purification
anticancer application
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021040167
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