HIV risk profile and prevention needs of individuals seeking monkeypox (mpox) vaccination in an urban clinic in the U.S.: a brief report
Abstract Background Our study survey assessed HIV risk profile and pre-exposure prophylaxis (PrEP) use among HIV-negative individuals seeking mpox vaccination, elucidating HIV prevention gaps and opportunities. Methods Anonymous cross-sectional surveys were self-administered at an urban academic cen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-03-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-023-08075-5 |
| _version_ | 1797846091719245824 |
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| author | Onyema Ogbuagu Manas Sharma Grace Igiraneza Laurie Andrews Jessica Tuan Lydia A. Barakat |
| author_facet | Onyema Ogbuagu Manas Sharma Grace Igiraneza Laurie Andrews Jessica Tuan Lydia A. Barakat |
| author_sort | Onyema Ogbuagu |
| collection | DOAJ |
| description | Abstract Background Our study survey assessed HIV risk profile and pre-exposure prophylaxis (PrEP) use among HIV-negative individuals seeking mpox vaccination, elucidating HIV prevention gaps and opportunities. Methods Anonymous cross-sectional surveys were self-administered at an urban academic center clinic in New Haven, CT, U.S. (August 18–November 18, 2022). Inclusion criteria included adults presenting for mpox vaccination who consented to the study. The study assessed STI risk (sexual practices, STI history, substance use). For HIV-negative participants, PrEP knowledge, attitudes, and preferences were assessed. Results Eighty-one of 210 individuals approached completed surveys (survey acceptance and completion rate 38.6%). Majority were cisgender-male (76/81; 93.8%), Caucasian (48/79; 60.8%), with median age 28 years (IQR-15). Nine of 81 (11.5%) self-reported HIV-positivity. Median sexual partner number (6 months prior) was 4 (IQR-5.8). Majority, 89.9% and 75.9%, reported insertive and receptive anal intercourse, respectively. 41% reported lifetime STI history, of whom 12.3% had an STI 6 months prior. Majority (55.8%) used ≥ 1 illicit substance; 87.7% moderate alcohol use. Among HIV-negative respondents, most (95.7%) were aware of PrEP, but only 48.4% used PrEP. Conclusion Individuals seeking mpox vaccination engage in behaviors placing them at increased STI risk and would benefit from PrEP assessment. |
| first_indexed | 2024-04-09T17:49:20Z |
| format | Article |
| id | doaj.art-7bce6c15b2b346b8bf269f4184df2932 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-09T17:49:20Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-7bce6c15b2b346b8bf269f4184df29322023-04-16T11:07:56ZengBMCBMC Infectious Diseases1471-23342023-03-012311710.1186/s12879-023-08075-5HIV risk profile and prevention needs of individuals seeking monkeypox (mpox) vaccination in an urban clinic in the U.S.: a brief reportOnyema Ogbuagu0Manas Sharma1Grace Igiraneza2Laurie Andrews3Jessica Tuan4Lydia A. Barakat5Section of Infectious Diseases, Yale School of MedicineSection of Infectious Diseases, Yale Department of Medicine, Yale School of Medicine, Yale University School of MedicineSection of Infectious Diseases, Yale Department of Medicine, Yale School of Medicine, Yale University School of MedicineSection of Infectious Diseases, Yale School of MedicineSection of Infectious Diseases, Yale School of MedicineSection of Infectious Diseases, Yale School of MedicineAbstract Background Our study survey assessed HIV risk profile and pre-exposure prophylaxis (PrEP) use among HIV-negative individuals seeking mpox vaccination, elucidating HIV prevention gaps and opportunities. Methods Anonymous cross-sectional surveys were self-administered at an urban academic center clinic in New Haven, CT, U.S. (August 18–November 18, 2022). Inclusion criteria included adults presenting for mpox vaccination who consented to the study. The study assessed STI risk (sexual practices, STI history, substance use). For HIV-negative participants, PrEP knowledge, attitudes, and preferences were assessed. Results Eighty-one of 210 individuals approached completed surveys (survey acceptance and completion rate 38.6%). Majority were cisgender-male (76/81; 93.8%), Caucasian (48/79; 60.8%), with median age 28 years (IQR-15). Nine of 81 (11.5%) self-reported HIV-positivity. Median sexual partner number (6 months prior) was 4 (IQR-5.8). Majority, 89.9% and 75.9%, reported insertive and receptive anal intercourse, respectively. 41% reported lifetime STI history, of whom 12.3% had an STI 6 months prior. Majority (55.8%) used ≥ 1 illicit substance; 87.7% moderate alcohol use. Among HIV-negative respondents, most (95.7%) were aware of PrEP, but only 48.4% used PrEP. Conclusion Individuals seeking mpox vaccination engage in behaviors placing them at increased STI risk and would benefit from PrEP assessment.https://doi.org/10.1186/s12879-023-08075-5MonkeypoxHIV infectionPre-exposure prophylaxisPrEPVaccination |
| spellingShingle | Onyema Ogbuagu Manas Sharma Grace Igiraneza Laurie Andrews Jessica Tuan Lydia A. Barakat HIV risk profile and prevention needs of individuals seeking monkeypox (mpox) vaccination in an urban clinic in the U.S.: a brief report BMC Infectious Diseases Monkeypox HIV infection Pre-exposure prophylaxis PrEP Vaccination |
| title | HIV risk profile and prevention needs of individuals seeking monkeypox (mpox) vaccination in an urban clinic in the U.S.: a brief report |
| title_full | HIV risk profile and prevention needs of individuals seeking monkeypox (mpox) vaccination in an urban clinic in the U.S.: a brief report |
| title_fullStr | HIV risk profile and prevention needs of individuals seeking monkeypox (mpox) vaccination in an urban clinic in the U.S.: a brief report |
| title_full_unstemmed | HIV risk profile and prevention needs of individuals seeking monkeypox (mpox) vaccination in an urban clinic in the U.S.: a brief report |
| title_short | HIV risk profile and prevention needs of individuals seeking monkeypox (mpox) vaccination in an urban clinic in the U.S.: a brief report |
| title_sort | hiv risk profile and prevention needs of individuals seeking monkeypox mpox vaccination in an urban clinic in the u s a brief report |
| topic | Monkeypox HIV infection Pre-exposure prophylaxis PrEP Vaccination |
| url | https://doi.org/10.1186/s12879-023-08075-5 |
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