When blood is thinner than water
Antagonists of vitamin K dependant clotting factors are commonly used as treatment/prophylaxis for anticoagulation. Due to their narrow therapeutic window, a wide range of complications including death may occur. International normalized ratio (INR) is monitored to measure adequacy/excess of anticoa...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Annals of Cardiac Anaesthesia |
| Subjects: | |
| Online Access: | http://www.annals.in/article.asp?issn=0971-9784;year=2013;volume=16;issue=1;spage=63;epage=65;aulast=Gude |
| _version_ | 1811258916836737024 |
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| author | Dilip Gude Aslam Abbas Hina Mohiuddin |
| author_facet | Dilip Gude Aslam Abbas Hina Mohiuddin |
| author_sort | Dilip Gude |
| collection | DOAJ |
| description | Antagonists of vitamin K dependant clotting factors are commonly used as treatment/prophylaxis for anticoagulation. Due to their narrow therapeutic window, a wide range of complications including death may occur. International normalized ratio (INR) is monitored to measure adequacy/excess of anticoagulation. There is a plethora of risk factors that may contribute to the uncontrollably high INR values. We describe our experience of a case of deep venous thrombosis wherein the patient had an overshoot of INR during anticoagulation therapy. We review the literature and discuss management in such scenarios. |
| first_indexed | 2024-04-12T18:21:43Z |
| format | Article |
| id | doaj.art-7bd26a7d807d4ebea0b561e490b8bf25 |
| institution | Directory Open Access Journal |
| issn | 0971-9784 |
| language | English |
| last_indexed | 2024-04-12T18:21:43Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Cardiac Anaesthesia |
| spelling | doaj.art-7bd26a7d807d4ebea0b561e490b8bf252022-12-22T03:21:24ZengWolters Kluwer Medknow PublicationsAnnals of Cardiac Anaesthesia0971-97842013-01-01161636510.4103/0971-9784.105375When blood is thinner than waterDilip GudeAslam AbbasHina MohiuddinAntagonists of vitamin K dependant clotting factors are commonly used as treatment/prophylaxis for anticoagulation. Due to their narrow therapeutic window, a wide range of complications including death may occur. International normalized ratio (INR) is monitored to measure adequacy/excess of anticoagulation. There is a plethora of risk factors that may contribute to the uncontrollably high INR values. We describe our experience of a case of deep venous thrombosis wherein the patient had an overshoot of INR during anticoagulation therapy. We review the literature and discuss management in such scenarios.http://www.annals.in/article.asp?issn=0971-9784;year=2013;volume=16;issue=1;spage=63;epage=65;aulast=GudeAnticoagulationBleedingInternational normalized ratio |
| spellingShingle | Dilip Gude Aslam Abbas Hina Mohiuddin When blood is thinner than water Annals of Cardiac Anaesthesia Anticoagulation Bleeding International normalized ratio |
| title | When blood is thinner than water |
| title_full | When blood is thinner than water |
| title_fullStr | When blood is thinner than water |
| title_full_unstemmed | When blood is thinner than water |
| title_short | When blood is thinner than water |
| title_sort | when blood is thinner than water |
| topic | Anticoagulation Bleeding International normalized ratio |
| url | http://www.annals.in/article.asp?issn=0971-9784;year=2013;volume=16;issue=1;spage=63;epage=65;aulast=Gude |
| work_keys_str_mv | AT dilipgude whenbloodisthinnerthanwater AT aslamabbas whenbloodisthinnerthanwater AT hinamohiuddin whenbloodisthinnerthanwater |