Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Abstract Background WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G...

书目详细资料
Main Authors:	Bashan Zhang, Rong Li, Wenfeng Wang, Xueming Zhou, Beijing Luo, Zinian Zhu, Xibo Zhang, Aijiao Ding
格式:	文件
语言:	English
出版:	BMC 2021-06-01
丛编:	Journal of Orthopaedic Surgery and Research
主题:	Osteogenesis imperfecta Osteoblast WNT1 Mutation β-Catenin
在线阅读:	https://doi.org/10.1186/s13018-021-02495-2

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