Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Abstract Background WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G...

書誌詳細
主要な著者:	Bashan Zhang, Rong Li, Wenfeng Wang, Xueming Zhou, Beijing Luo, Zinian Zhu, Xibo Zhang, Aijiao Ding
フォーマット:	論文
言語:	English
出版事項:	BMC 2021-06-01
シリーズ:	Journal of Orthopaedic Surgery and Research
主題:	Osteogenesis imperfecta Osteoblast WNT1 Mutation β-Catenin
オンライン･アクセス:	https://doi.org/10.1186/s13018-021-02495-2

類似資料

Risperidone induces apoptosis of human osteoblast cell line hFob1.19 through Wnt/β-catenin signaling pathway
著者:: PANG Lan, LI Peifan, ZHENG Lei, WANG Yiming
出版事項: (2023-03-01)

Regulation of Osteoblast Metabolism by Wnt Signaling
著者:: Megan C. Moorer, 等
出版事項: (2018-08-01)

Atypical antipsychotics induce human osteoblasts apoptosis via Wnt/β-catenin signaling
著者:: Peifan Li, 等
出版事項: (2019-02-01)

Novel mutation G324C in WNT1 mapped in a large Pakistani family with severe recessively inherited Osteogenesis Imperfecta
著者:: Mehran Kausar, 等
出版事項: (2018-11-01)

Mandible and iliac osteoblasts exhibit different Wnt signaling responses to LMHF vibration
著者:: Anute Pravitharangul, 等
出版事項: (2019-10-01)

Andrographolide Exerts Pro-Osteogenic Effect by Activation of Wnt/β-Catenin Signaling Pathway in Vitro
著者:: Tongmeng Jiang, 等
出版事項: (2015-07-01)

Extremely low-frequency electromagnetic fields facilitate both osteoblast and osteoclast activity through Wnt/β-catenin signaling in the zebrafish scale
著者:: Jingjing Kobayashi-Sun, 等
出版事項: (2024-02-01)

Protective Effects of Pretreatment with Quercetin Against Lipopolysaccharide-Induced Apoptosis and the Inhibition of Osteoblast Differentiation via the MAPK and Wnt/β-Catenin Pathways in MC3T3-E1 Cells
著者:: Chun Guo, 等
出版事項: (2017-10-01)

Celecoxib inhibits osteoblast maturation by suppressing the expression of Wnt target genes
著者:: Akihiro Nagano, 等
出版事項: (2017-01-01)

Reciprocal Interferences of TNF-α and Wnt1/β-Catenin Signaling Axes Shift Bone Marrow-Derived Stem Cells Towards Osteoblast Lineage after Ethanol Exposure
著者:: Yueping Chen, 等
出版事項: (2013-09-01)

Spatiotemporal Analysis of Osteoblast Morphology and Wnt Signal‐Induced Osteoblast Reactivation during Bone Modeling in Vitro
著者:: Naoki Tsuji, 等
出版事項: (2022-11-01)

Deciphering Myostatin’s Regulatory, Metabolic, and Developmental Influence in Skeletal Diseases
著者:: Catherine L. Omosule, 等
出版事項: (2021-03-01)

ED-71 Prevents Glucocorticoid-Induced Osteoporosis by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways
著者:: Rong X, 等
出版事項: (2022-11-01)

Roxadustat promotes osteoblast differentiation and prevents estrogen deficiency-induced bone loss by stabilizing HIF-1α and activating the Wnt/β-catenin signaling pathway
著者:: Luyao Li, 等
出版事項: (2022-05-01)

ZEB1 Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation Partly via Wnt/β-Catenin Signaling
著者:: Cuidi Xu, 等
出版事項: (2021-05-01)

EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/β-catenin signaling
著者:: Junjie Shen, 等
出版事項: (2021-07-01)

Nystose attenuates bone loss and promotes BMSCs differentiation to osteoblasts through BMP and Wnt/β-catenin pathway in ovariectomized mice
著者:: Qi Zhang, 等
出版事項: (2023-03-01)

Synergistic Effects of Erzhi Pill Combined With Methotrexate on Osteoblasts Mediated via the Wnt1/LRP5/β-Catenin Signaling Pathway in Collagen-Induced Arthritis Rats
著者:: Xiaoya Li, 等
出版事項: (2020-03-01)

Roles of Wnt signaling in bone formation and resorption
著者:: Yasuhiro Kobayashi, 等
出版事項: (2008-07-01)

Lanthanum phosphate/chitosan scaffolds enhance cytocompatibility and osteogenic efficiency via the Wnt/β-catenin pathway
著者:: Haoran Hu, 等
出版事項: (2018-11-01)

Sodium selenite promotes osteoblast differentiation via the WNT/β-catenin signaling pathway
著者:: Ashish Ranjan Sharma, 等
出版事項: (2022-06-01)

Severe osteogenesis imperfecta: case report
著者:: Fernando Bastos, 等
出版事項: (2010-12-01)

Severe osteogenesis imperfecta: case report
著者:: Fernando Bastos, 等
出版事項: (2010-12-01)

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation
著者:: Olga Gewartowska, 等
出版事項: (2021-04-01)

Wnt/β-catenin signaling pathway: proteins' roles in osteoporosis and cancer diseases and the regulatory effects of natural compounds on osteoporosis
著者:: Xiaohao Wang, 等
出版事項: (2024-10-01)

Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene
著者:: Maria Cristina Campopiano, 等
出版事項: (2022-08-01)

Wnt Signaling in the Development of Bone Metastasis
著者:: Noa Ben-Ghedalia-Peled, 等
出版事項: (2022-12-01)

Osteogenesis Imperfecta: New Perspectives From Clinical and Translational Research
著者:: Josephine T Tauer, 等
出版事項: (2019-08-01)

Cajanolactone A from Cajanus cajan Promoted Osteoblast Differentiation in Human Bone Marrow Mesenchymal Stem Cells via Stimulating Wnt/LRP5/β-Catenin Signaling
著者:: Shan Liu, 等
出版事項: (2019-01-01)

LncRNA KCNQ1OT1 promotes osteogenic differentiation to relieve osteolysis via Wnt/β-catenin activation
著者:: Xuren Gao, 等
出版事項: (2018-03-01)

Osteoblasts mineralization and collagen matrix are conserved upon specific Col1a2 silencing
著者:: Silvia Maruelli, 等
出版事項: (2020-05-01)

Chrysosplenetin promotes osteoblastogenesis of bone marrow stromal cells via Wnt/β-catenin pathway and enhances osteogenesis in estrogen deficiency-induced bone loss
著者:: Guoju Hong, 等
出版事項: (2019-08-01)

The most 5′ truncating homozygous mutation of WNT1 in siblings with osteogenesis imperfecta with a variable degree of brain anomalies: a case report
著者:: Chulaluck Kuptanon, 等
出版事項: (2018-07-01)

Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children
著者:: Huong Thi Thu Nguyen, 等
出版事項: (2021-04-01)

Osteogenesis imperfecta and dentinogenesis imperfecta: Clinical features and dental management
著者:: Chetna Grover, 等
出版事項: (2022-01-01)

Osteogénesis imperfecta forma clásica no deformante. Comunicación de una nueva mutación en el gen COL1A1 en dos casos de la misma familia
著者:: Pavón de Paz I, 等
出版事項: (2016-02-01)

Erythropoietin enhances osteogenic differentiation of human periodontal ligament stem cells via Wnt/β-catenin signaling pathway
著者:: Zheng DH, 等
出版事項: (2019-07-01)

The protective effect of piperine on ovariectomy induced bone loss in female mice and its enhancement effect of osteogenic differentiation via Wnt/β-catenin signaling pathway
著者:: Chenrui Li, 等
出版事項: (2019-07-01)

Wnt1 and β-Catenin Expression in Lobular Capillary Hemangioma: Immunohistochemical Study
著者:: Esma İnan Yüksel, 等
出版事項: (2023-08-01)

ER, Mitochondria, and ISR Regulation by mt‐HSP70 and ATF5 upon Procollagen Misfolding in Osteoblasts
著者:: Laura Gorrell, 等
出版事項: (2022-10-01)