Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Abstract Background WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Bashan Zhang, Rong Li, Wenfeng Wang, Xueming Zhou, Beijing Luo, Zinian Zhu, Xibo Zhang, Aijiao Ding
Format:	Artykuł
Język:	English
Wydane:	BMC 2021-06-01
Seria:	Journal of Orthopaedic Surgery and Research
Hasła przedmiotowe:	Osteogenesis imperfecta Osteoblast WNT1 Mutation β-Catenin
Dostęp online:	https://doi.org/10.1186/s13018-021-02495-2

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