Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Abstract Background WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G...

Полное описание

Библиографические подробности
Главные авторы:	Bashan Zhang, Rong Li, Wenfeng Wang, Xueming Zhou, Beijing Luo, Zinian Zhu, Xibo Zhang, Aijiao Ding
Формат:	Статья
Язык:	English
Опубликовано:	BMC 2021-06-01
Серии:	Journal of Orthopaedic Surgery and Research
Предметы:	Osteogenesis imperfecta Osteoblast WNT1 Mutation β-Catenin
Online-ссылка:	https://doi.org/10.1186/s13018-021-02495-2

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