Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Abstract Background WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G...

書目詳細資料
Main Authors:	Bashan Zhang, Rong Li, Wenfeng Wang, Xueming Zhou, Beijing Luo, Zinian Zhu, Xibo Zhang, Aijiao Ding
格式:	Article
語言:	English
出版:	BMC 2021-06-01
叢編:	Journal of Orthopaedic Surgery and Research
主題:	Osteogenesis imperfecta Osteoblast WNT1 Mutation β-Catenin
在線閱讀:	https://doi.org/10.1186/s13018-021-02495-2

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