Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway
Abstract Background WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G...
| Κύριοι συγγραφείς: | , , , , , , , |
|---|---|
| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
BMC
2021-06-01
|
| Σειρά: | Journal of Orthopaedic Surgery and Research |
| Θέματα: | |
| Διαθέσιμο Online: | https://doi.org/10.1186/s13018-021-02495-2 |