Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Abstract Background WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Bashan Zhang, Rong Li, Wenfeng Wang, Xueming Zhou, Beijing Luo, Zinian Zhu, Xibo Zhang, Aijiao Ding
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: BMC 2021-06-01
Цуврал:Journal of Orthopaedic Surgery and Research
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1186/s13018-021-02495-2