Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

Abstract Background WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G...

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Chi tiết về thư mục
Những tác giả chính: Bashan Zhang, Rong Li, Wenfeng Wang, Xueming Zhou, Beijing Luo, Zinian Zhu, Xibo Zhang, Aijiao Ding
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: BMC 2021-06-01
Loạt:Journal of Orthopaedic Surgery and Research
Những chủ đề:
Osteogenesis imperfecta
Osteoblast
WNT1
Mutation
β-Catenin
Truy cập trực tuyến:https://doi.org/10.1186/s13018-021-02495-2

Internet

https://doi.org/10.1186/s13018-021-02495-2

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