Current Knowledge in Ultrasound-Based Liver Elastography of Pediatric Patients
Studies performed using transient elastography (TE), point shear wave elastography (pSWE) and two-dimensional shear wave elastography (2D-SWE) have shown that these techniques are all feasible and accurate in children for the evaluation of liver fibrosis due to several etiologies. However, for some...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-06-01
|
| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-3417/8/6/944 |
| _version_ | 1818354062597292032 |
|---|---|
| author | Christoph F. Dietrich Roxana Sirli Giovanna Ferraioli Alina Popescu Ioan Sporea Corina Pienar Christian Kunze Heike Taut Simone Schrading Simona Bota Dagmar Schreiber-Dietrich Dong Yi |
| author_facet | Christoph F. Dietrich Roxana Sirli Giovanna Ferraioli Alina Popescu Ioan Sporea Corina Pienar Christian Kunze Heike Taut Simone Schrading Simona Bota Dagmar Schreiber-Dietrich Dong Yi |
| author_sort | Christoph F. Dietrich |
| collection | DOAJ |
| description | Studies performed using transient elastography (TE), point shear wave elastography (pSWE) and two-dimensional shear wave elastography (2D-SWE) have shown that these techniques are all feasible and accurate in children for the evaluation of liver fibrosis due to several etiologies. However, for some specific pediatric pathologies, such as biliary atresia, the evidence is still limited. As shown in adults, inflammation is a confounding factor when assessing fibrosis severity and care should be taken when interpreting the results. Due to the scarce comparative data between serological tests and elastography techniques in children, a definite conclusion regarding which is the best cannot be drawn. Neither non-invasive elastographic techniques nor laboratory scores allow determination of the presence and the degree of inflammation, necrosis, iron or copper deposits. |
| first_indexed | 2024-12-13T19:19:27Z |
| format | Article |
| id | doaj.art-7bd3e8e180314878b9d6834c6e7c3737 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-12-13T19:19:27Z |
| publishDate | 2018-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-7bd3e8e180314878b9d6834c6e7c37372022-12-21T23:34:12ZengMDPI AGApplied Sciences2076-34172018-06-018694410.3390/app8060944app8060944Current Knowledge in Ultrasound-Based Liver Elastography of Pediatric PatientsChristoph F. Dietrich0Roxana Sirli1Giovanna Ferraioli2Alina Popescu3Ioan Sporea4Corina Pienar5Christian Kunze6Heike Taut7Simone Schrading8Simona Bota9Dagmar Schreiber-Dietrich10Dong Yi11Medizinische Klinik 2, Caritas-Krankenhaus Bad Mergentheim, Uhlandstraße 7, 97980 Bad Mergentheim, GermanyDepartment of Gastroenterology and Hepatology, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 300041 Timișoara, RomaniaUltrasound Unit, Clinical Sciences and Infectious Diseases Department, Fondazione IRCCS Policlinico San Matteo, Medical School University of Pavia, 27100 Pavia, ItalyDepartment of Gastroenterology and Hepatology, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 300041 Timișoara, RomaniaDepartment of Gastroenterology and Hepatology, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 300041 Timișoara, RomaniaPediatrics Department, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 300041 Timișoara, RomaniaKlinik für Radiologie, Abteilung Kinderradiologie, Universitätsklinikum Halle (Saale), Martin-Luther-Universität Halle-Wittenberg, 06120 Halle, GermanyKlinik und Poliklinik für Kinder-und Jugendmedizin, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, 01307 Dresden, GermanyKlinik für Diagnostische und Interventionelle Radiologie, University of Aachen, 52062 Aachen, GermanyDepartment of Gastroenterology, Hepatology, Nephrology and Endocrinology, Klinikum Klagenfurt am Wörthersee, 9020 Klagenfurt am Wörthersee, AustriaMedizinische Klinik 2, Caritas-Krankenhaus Bad Mergentheim, Uhlandstraße 7, 97980 Bad Mergentheim, GermanyDepartment of ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200433, ChinaStudies performed using transient elastography (TE), point shear wave elastography (pSWE) and two-dimensional shear wave elastography (2D-SWE) have shown that these techniques are all feasible and accurate in children for the evaluation of liver fibrosis due to several etiologies. However, for some specific pediatric pathologies, such as biliary atresia, the evidence is still limited. As shown in adults, inflammation is a confounding factor when assessing fibrosis severity and care should be taken when interpreting the results. Due to the scarce comparative data between serological tests and elastography techniques in children, a definite conclusion regarding which is the best cannot be drawn. Neither non-invasive elastographic techniques nor laboratory scores allow determination of the presence and the degree of inflammation, necrosis, iron or copper deposits.http://www.mdpi.com/2076-3417/8/6/944ultrasound elastographypediatricliver fibrosisstiffnessshear wave elastography (SWE) |
| spellingShingle | Christoph F. Dietrich Roxana Sirli Giovanna Ferraioli Alina Popescu Ioan Sporea Corina Pienar Christian Kunze Heike Taut Simone Schrading Simona Bota Dagmar Schreiber-Dietrich Dong Yi Current Knowledge in Ultrasound-Based Liver Elastography of Pediatric Patients Applied Sciences ultrasound elastography pediatric liver fibrosis stiffness shear wave elastography (SWE) |
| title | Current Knowledge in Ultrasound-Based Liver Elastography of Pediatric Patients |
| title_full | Current Knowledge in Ultrasound-Based Liver Elastography of Pediatric Patients |
| title_fullStr | Current Knowledge in Ultrasound-Based Liver Elastography of Pediatric Patients |
| title_full_unstemmed | Current Knowledge in Ultrasound-Based Liver Elastography of Pediatric Patients |
| title_short | Current Knowledge in Ultrasound-Based Liver Elastography of Pediatric Patients |
| title_sort | current knowledge in ultrasound based liver elastography of pediatric patients |
| topic | ultrasound elastography pediatric liver fibrosis stiffness shear wave elastography (SWE) |
| url | http://www.mdpi.com/2076-3417/8/6/944 |
| work_keys_str_mv | AT christophfdietrich currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT roxanasirli currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT giovannaferraioli currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT alinapopescu currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT ioansporea currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT corinapienar currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT christiankunze currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT heiketaut currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT simoneschrading currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT simonabota currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT dagmarschreiberdietrich currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients AT dongyi currentknowledgeinultrasoundbasedliverelastographyofpediatricpatients |