Synthesis of PAMAM dendrimers with porphyrin core and functionalized periphery as templates of metal composite materials and their toxicity evaluation
Experiments were performed for the synthesis of meso-substituted tetraphenyl porphyrins in order to obtain growth active points for PAMAM branches and a functionalized periphery with thiazole groups for increasing the metal complexation activity. Characterization by 1H and 13C NMR, mass spectrometry...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-01-01
|
| Series: | Arabian Journal of Chemistry |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535217300321 |
| Summary: | Experiments were performed for the synthesis of meso-substituted tetraphenyl porphyrins in order to obtain growth active points for PAMAM branches and a functionalized periphery with thiazole groups for increasing the metal complexation activity. Characterization by 1H and 13C NMR, mass spectrometry and infrared spectrometry confirmed the produced dendrimeric nanostructures; the chemical reduction of metallic Ag and Cu inside the dendrimer was proved by XPS. Finally, the toxicity of the metal-dendrimer complex was analyzed by means of the bacterial respiration test. Keywords: Porphyrin, PAMAM-dendrimers, Metal complex, Metal species |
|---|---|
| ISSN: | 1878-5352 |