Eliminating the VGlut2-Dependent Glutamatergic Transmission of Parvalbumin-Expressing Neurons Leads to Deficits in Locomotion and Vocalization, Decreased Pain Sensitivity, and Increased Dominance

Eliminating the VGlut2-Dependent Glutamatergic Transmission of Parvalbumin-Expressing Neurons Leads to Deficits in Locomotion and Vocalization, Decreased Pain Sensitivity, and Increased Dominance

The calcium-binding protein parvalbumin (PV) is a recognized marker of short-axon GABA-ergic neurons in the cortex and the hippocampus. However in addition, PV is expressed by excitatory, glutamatergic neurons in various areas of the brain and spinal cord. Depending on the location of these neurons,...

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Bibliographic Details
Main Authors: Diana M. Roccaro-Waldmeyer, Franck Girard, Daniele Milani, Elisabetta Vannoni, Laurent Prétôt, David P. Wolfer, Marco R. Celio
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
parvalbumin
VGlut2
Cre/Lox-system
pain
ultrasonic vocalization
dominance
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2018.00146/full

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