5-Hydroxymethylcytosines in circulating cell-free DNA reveal a diagnostic biomarker for glioma

5-Hydroxymethylcytosines in circulating cell-free DNA reveal a diagnostic biomarker for glioma

Gliomas typically have unfavorable prognosis, due to late detection and interventions. However, effective biomarkers for early glioma diagnosis based on 5-hydroxymethylcytosines (5 hm C) in circulating cell-free DNA (cfDNA) are not currently available. 5 hm C profiles in GSE132118 set were subjected...

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Bibliographic Details
Main Authors: Chunyu Zhang, Wei Zhou, Yinqiu Tan, Daofeng Tian, Chunlong Zhong
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Heliyon
Subjects:
Diagnostic biomarker
cfDNA
5 hm C
Glioma
LASSO
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022023106

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