Estimation of accuracy loss by training a deep-learning-based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution information

In collaboration with the Institute of Virology, Philipps University, Marburg, a deep-learning-based method that recognizes and classifies cell organelles based on the distribution of subviral particles in fluorescence microscopy images of virus-infected cells has been further developed. In this wor...

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Main Authors: Busch Nils, Rausch Andreas, Schanze Thomas
Format: Article
Language:English
Published: De Gruyter 2021-10-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2021-2047
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author Busch Nils
Rausch Andreas
Schanze Thomas
author_facet Busch Nils
Rausch Andreas
Schanze Thomas
author_sort Busch Nils
collection DOAJ
description In collaboration with the Institute of Virology, Philipps University, Marburg, a deep-learning-based method that recognizes and classifies cell organelles based on the distribution of subviral particles in fluorescence microscopy images of virus-infected cells has been further developed. In this work a method to recognize cell organelles by means of partial image information is extended. The focus is on investigating loss of accuracy by only providing information about subviral particles and not all cell organelles to an adopted Mask-R convolutional neural network. Our results show that the subviral particle distribution holds information about the cell morphology, thus making it possible to use it for cell organelle-labelling.
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spelling doaj.art-7bd7a93e362f4e6fb90f0ebb029713172022-12-22T03:28:07ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042021-10-017218318610.1515/cdbme-2021-2047Estimation of accuracy loss by training a deep-learning-based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution informationBusch Nils0Rausch Andreas1Schanze Thomas2Institute for Biomedical Engineering (IBMT), Faculty of Life Science Engineering (LSE), Technische Hochschule Mittelhessen (THM) - University of Applied Sciences,Gießen, GermanyInstitute for Biomedical Engineering (IBMT), Faculty of Life Science Engineering (LSE), Technische Hochschule Mittelhessen (THM) - University of Applied Sciences,Gießen, GermanyInstitute for Biomedical Engineering (IBMT), Faculty of Life Science Engineering (LSE), Technische Hochschule Mittelhessen (THM) - University of Applied Sciences,Gießen, GermanyIn collaboration with the Institute of Virology, Philipps University, Marburg, a deep-learning-based method that recognizes and classifies cell organelles based on the distribution of subviral particles in fluorescence microscopy images of virus-infected cells has been further developed. In this work a method to recognize cell organelles by means of partial image information is extended. The focus is on investigating loss of accuracy by only providing information about subviral particles and not all cell organelles to an adopted Mask-R convolutional neural network. Our results show that the subviral particle distribution holds information about the cell morphology, thus making it possible to use it for cell organelle-labelling.https://doi.org/10.1515/cdbme-2021-2047deep-learningobject detectionsubviral particles.
spellingShingle Busch Nils
Rausch Andreas
Schanze Thomas
Estimation of accuracy loss by training a deep-learning-based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution information
Current Directions in Biomedical Engineering
deep-learning
object detection
subviral particles.
title Estimation of accuracy loss by training a deep-learning-based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution information
title_full Estimation of accuracy loss by training a deep-learning-based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution information
title_fullStr Estimation of accuracy loss by training a deep-learning-based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution information
title_full_unstemmed Estimation of accuracy loss by training a deep-learning-based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution information
title_short Estimation of accuracy loss by training a deep-learning-based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution information
title_sort estimation of accuracy loss by training a deep learning based cell organelle recognition software using full dataset and a reduced dataset containing only subviral particle distribution information
topic deep-learning
object detection
subviral particles.
url https://doi.org/10.1515/cdbme-2021-2047
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