Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells--possible relevance to autism spectrum disorders.

Alterations in gut microbiome composition have an emerging role in health and disease including brain function and behavior. Short chain fatty acids (SCFA) like propionic (PPA), and butyric acid (BA), which are present in diet and are fermentation products of many gastrointestinal bacteria, are show...

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书目详细资料
Main Authors: Bistra B Nankova, Raj Agarwal, Derrick F MacFabe, Edmund F La Gamma
格式: 文件
语言:English
出版: Public Library of Science (PLoS) 2014-01-01
丛编:PLoS ONE
在线阅读:http://europepmc.org/articles/PMC4149359?pdf=render