Neuroinflammation following anti-parkinsonian drugs in early Parkinson’s disease: a longitudinal PET study

Neuroinflammation following anti-parkinsonian drugs in early Parkinson’s disease: a longitudinal PET study

Abstract The progression of neuroinflammation after anti-parkinsonian therapy on the Parkinson’s disease (PD) brain and in vivo evidence of the therapy purporting neuroprotection remain unclear. To elucidate this, we examined changes in microglial activation, nigrostriatal degeneration, and clinical...

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Bibliographic Details
Main Authors: Tatsuhiro Terada, Tomoyasu Bunai, Takanori Hashizume, Takashi Matsudaira, Masamichi Yokokura, Hirotsugu Takashima, Takashi Konishi, Tomokazu Obi, Yasuomi Ouchi
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Parkinson’s disease (PD)
Neuroinflammation
Dopamine transporter
Zonisamide
Positron emission tomography
Online Access:https://doi.org/10.1038/s41598-024-55233-z

Internet

https://doi.org/10.1038/s41598-024-55233-z

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