MiR-99a alleviates apoptosis and extracellular matrix degradation in experimentally induced spine osteoarthritis by targeting FZD8

MiR-99a alleviates apoptosis and extracellular matrix degradation in experimentally induced spine osteoarthritis by targeting FZD8

Abstract Background Our previous study identified miR-99a as a negative regulator of early chondrogenic differentiation. However, the functional role of miR-99a in the pathogenesis of osteoarthritis (OA) remains unclear. Methods We examined the levels of miR-99a and Frizzled 8 (FZD8) expression in t...

Full description

Bibliographic Details
Main Authors: Yeyang Wang, Xiaoyu Zheng, Dixin Luo, Wangyang Xu, Xiaozhong Zhou
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Musculoskeletal Disorders
Subjects:
Osteoarthritis
miR-99a
FZD8
Apoptosis
Extracellular matrix degradation
Online Access:https://doi.org/10.1186/s12891-022-05822-8

Internet

https://doi.org/10.1186/s12891-022-05822-8

Similar Items