ANTIOXIDANT ACTIVITY OF GINGER (Zingiber officinale) OLEORESIN ON THE PROFILE OF SUPEROXIDE DISMUTASE (SOD) IN THE KIDNEY OF RATS UNDER STRESS CONDITION

Stress condition has beeb reported to decrease intracellular antioxidant-superoxide dismutase(SOD) in the liver and kidney of rats. This study was conducted to evaluate the antioxidant activies of ginger oleoresin on the profile of superoxide dismutase(SOD) in the kidney of rats under stress conditi...

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Main Authors: Tutik Wresdiyati1), Made Astawan2), Deddy Muchtadi2), Yana Nurdiana2)
Format: Article
Language:English
Published: Bogor Agricultural University; Indonesian Food Technologist Association (IAFT) 2007-12-01
Series:Jurnal Teknologi dan Industri Pangan
Subjects:
Online Access:http://journal.ipb.ac.id/index.php/jtip/article/view/396
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author Tutik Wresdiyati1)
Made Astawan2)
Deddy Muchtadi2)
Yana Nurdiana2)
author_facet Tutik Wresdiyati1)
Made Astawan2)
Deddy Muchtadi2)
Yana Nurdiana2)
author_sort Tutik Wresdiyati1)
collection DOAJ
description Stress condition has beeb reported to decrease intracellular antioxidant-superoxide dismutase(SOD) in the liver and kidney of rats. This study was conducted to evaluate the antioxidant activies of ginger oleoresin on the profile of superoxide dismutase(SOD) in the kidney of rats under stress condition. The stress condition was achieved by five days of fasting together with swimming for 5 min/day. Ginger oleoresin was orally administrated in a dose of 60 mg/KgBW/day for seven days. Drinking water was provided ad libitum to all groups. The treatment of ginger oleoresin significantly decreased malondialdehyde (MDA) levels and increased SOD activity, as well as immunohistochemicall, increased the content of copper, zinc-SOD (Cu, Zn-SOD) in the kidney tissues compared to that of untreated group. The antioxidant content in ginger oleoresin such as shogaol, zingeron, and gingerol, etc. were shownto have activities in the kidney tissues of rats under stress condition that is increasunf the profile of SOD. Ginger oleoresin treatment in combination both before and after stress gave the best result.
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spelling doaj.art-7bdb8d9a984a4aaf981b8354e55c18b42022-12-21T20:11:09ZengBogor Agricultural University; Indonesian Food Technologist Association (IAFT)Jurnal Teknologi dan Industri Pangan1979-77882087-751X2007-12-01182118125ANTIOXIDANT ACTIVITY OF GINGER (Zingiber officinale) OLEORESIN ON THE PROFILE OF SUPEROXIDE DISMUTASE (SOD) IN THE KIDNEY OF RATS UNDER STRESS CONDITIONTutik Wresdiyati1)Made Astawan2)Deddy Muchtadi2)Yana Nurdiana2)Stress condition has beeb reported to decrease intracellular antioxidant-superoxide dismutase(SOD) in the liver and kidney of rats. This study was conducted to evaluate the antioxidant activies of ginger oleoresin on the profile of superoxide dismutase(SOD) in the kidney of rats under stress condition. The stress condition was achieved by five days of fasting together with swimming for 5 min/day. Ginger oleoresin was orally administrated in a dose of 60 mg/KgBW/day for seven days. Drinking water was provided ad libitum to all groups. The treatment of ginger oleoresin significantly decreased malondialdehyde (MDA) levels and increased SOD activity, as well as immunohistochemicall, increased the content of copper, zinc-SOD (Cu, Zn-SOD) in the kidney tissues compared to that of untreated group. The antioxidant content in ginger oleoresin such as shogaol, zingeron, and gingerol, etc. were shownto have activities in the kidney tissues of rats under stress condition that is increasunf the profile of SOD. Ginger oleoresin treatment in combination both before and after stress gave the best result.http://journal.ipb.ac.id/index.php/jtip/article/view/396antioxidantginger oleoresinkidneystresssuperoxide dismutase (SOD)
spellingShingle Tutik Wresdiyati1)
Made Astawan2)
Deddy Muchtadi2)
Yana Nurdiana2)
ANTIOXIDANT ACTIVITY OF GINGER (Zingiber officinale) OLEORESIN ON THE PROFILE OF SUPEROXIDE DISMUTASE (SOD) IN THE KIDNEY OF RATS UNDER STRESS CONDITION
Jurnal Teknologi dan Industri Pangan
antioxidant
ginger oleoresin
kidney
stress
superoxide dismutase (SOD)
title ANTIOXIDANT ACTIVITY OF GINGER (Zingiber officinale) OLEORESIN ON THE PROFILE OF SUPEROXIDE DISMUTASE (SOD) IN THE KIDNEY OF RATS UNDER STRESS CONDITION
title_full ANTIOXIDANT ACTIVITY OF GINGER (Zingiber officinale) OLEORESIN ON THE PROFILE OF SUPEROXIDE DISMUTASE (SOD) IN THE KIDNEY OF RATS UNDER STRESS CONDITION
title_fullStr ANTIOXIDANT ACTIVITY OF GINGER (Zingiber officinale) OLEORESIN ON THE PROFILE OF SUPEROXIDE DISMUTASE (SOD) IN THE KIDNEY OF RATS UNDER STRESS CONDITION
title_full_unstemmed ANTIOXIDANT ACTIVITY OF GINGER (Zingiber officinale) OLEORESIN ON THE PROFILE OF SUPEROXIDE DISMUTASE (SOD) IN THE KIDNEY OF RATS UNDER STRESS CONDITION
title_short ANTIOXIDANT ACTIVITY OF GINGER (Zingiber officinale) OLEORESIN ON THE PROFILE OF SUPEROXIDE DISMUTASE (SOD) IN THE KIDNEY OF RATS UNDER STRESS CONDITION
title_sort antioxidant activity of ginger zingiber officinale oleoresin on the profile of superoxide dismutase sod in the kidney of rats under stress condition
topic antioxidant
ginger oleoresin
kidney
stress
superoxide dismutase (SOD)
url http://journal.ipb.ac.id/index.php/jtip/article/view/396
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AT madeastawan2 antioxidantactivityofgingerzingiberofficinaleoleoresinontheprofileofsuperoxidedismutasesodinthekidneyofratsunderstresscondition
AT deddymuchtadi2 antioxidantactivityofgingerzingiberofficinaleoleoresinontheprofileofsuperoxidedismutasesodinthekidneyofratsunderstresscondition
AT yananurdiana2 antioxidantactivityofgingerzingiberofficinaleoleoresinontheprofileofsuperoxidedismutasesodinthekidneyofratsunderstresscondition