Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon Dots
Carbon dots (CDs) demonstrate very poor fluorescence quantum yield (QY). In this study, with the help of a hydrothermal method, we combined CDs with nitrogen and phosphorus elements belonging to the VA group (in the periodic table) to form heteroatom co-doped CDs, i.e., nitrogen and phosphorus co-do...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/12/3470 |
| _version_ | 1797564746565681152 |
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| author | Thi Hoa Le Hyun Jong Lee Ji Hyeon Kim Sang Joon Park |
| author_facet | Thi Hoa Le Hyun Jong Lee Ji Hyeon Kim Sang Joon Park |
| author_sort | Thi Hoa Le |
| collection | DOAJ |
| description | Carbon dots (CDs) demonstrate very poor fluorescence quantum yield (QY). In this study, with the help of a hydrothermal method, we combined CDs with nitrogen and phosphorus elements belonging to the VA group (in the periodic table) to form heteroatom co-doped CDs, i.e., nitrogen and phosphorus co-doped carbon dots (NPCDs). These displayed a significant improvement in the QY (up to 84%), which was as much as four times than that of CDs synthesized by the same method. The as-prepared NPCDs could be used as an “off-on” fluorescence detector for the rapid and effective sensing of ferric ions (Fe<sup>3+</sup>) and catecholamine neurotransmitters (CNs) such as dopamine (DA), adrenaline (AD), and noradrenaline (NAD). The fluorescence of NPCDs was “turned off” and the emission wavelength was slightly red-shifted upon increasing the Fe<sup>3+</sup> concentration. However, when CNs were incorporated, the fluorescence of NPCDs was recovered in a short response time; this indicated that CN concentration could be monitored, relying on enhancing the fluorescence signal of NPCDs. As a result, NPCDs are considered as a potential fluorescent bi-sensor for Fe<sup>3+</sup> and CN detection. Particularly, in this research, we selected DA as the representative neurotransmitter of the CN group along with Fe<sup>3+</sup> to study the sensing system based on NPCDs. The results exhibited good linear ranges with a limit of detection (LOD) of 0.2 and 0.1 µM for Fe<sup>3+</sup> and DA, respectively. |
| first_indexed | 2024-03-10T19:01:17Z |
| format | Article |
| id | doaj.art-7be25d5620d34d39a8f16f3d94643a08 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T19:01:17Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-7be25d5620d34d39a8f16f3d94643a082023-11-20T04:24:25ZengMDPI AGSensors1424-82202020-06-012012347010.3390/s20123470Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon DotsThi Hoa Le0Hyun Jong Lee1Ji Hyeon Kim2Sang Joon Park3Department of Chemical and Biological Engineering, Gachon University, Seongnam 13120, KoreaDepartment of Chemical and Biological Engineering, Gachon University, Seongnam 13120, KoreaDepartment of Chemical and Biological Engineering, Gachon University, Seongnam 13120, KoreaDepartment of Chemical and Biological Engineering, Gachon University, Seongnam 13120, KoreaCarbon dots (CDs) demonstrate very poor fluorescence quantum yield (QY). In this study, with the help of a hydrothermal method, we combined CDs with nitrogen and phosphorus elements belonging to the VA group (in the periodic table) to form heteroatom co-doped CDs, i.e., nitrogen and phosphorus co-doped carbon dots (NPCDs). These displayed a significant improvement in the QY (up to 84%), which was as much as four times than that of CDs synthesized by the same method. The as-prepared NPCDs could be used as an “off-on” fluorescence detector for the rapid and effective sensing of ferric ions (Fe<sup>3+</sup>) and catecholamine neurotransmitters (CNs) such as dopamine (DA), adrenaline (AD), and noradrenaline (NAD). The fluorescence of NPCDs was “turned off” and the emission wavelength was slightly red-shifted upon increasing the Fe<sup>3+</sup> concentration. However, when CNs were incorporated, the fluorescence of NPCDs was recovered in a short response time; this indicated that CN concentration could be monitored, relying on enhancing the fluorescence signal of NPCDs. As a result, NPCDs are considered as a potential fluorescent bi-sensor for Fe<sup>3+</sup> and CN detection. Particularly, in this research, we selected DA as the representative neurotransmitter of the CN group along with Fe<sup>3+</sup> to study the sensing system based on NPCDs. The results exhibited good linear ranges with a limit of detection (LOD) of 0.2 and 0.1 µM for Fe<sup>3+</sup> and DA, respectively.https://www.mdpi.com/1424-8220/20/12/3470off-on fluorescence detectorbi-sensorco-doped carbon dotsimproved quantum yield |
| spellingShingle | Thi Hoa Le Hyun Jong Lee Ji Hyeon Kim Sang Joon Park Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon Dots Sensors off-on fluorescence detector bi-sensor co-doped carbon dots improved quantum yield |
| title | Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon Dots |
| title_full | Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon Dots |
| title_fullStr | Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon Dots |
| title_full_unstemmed | Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon Dots |
| title_short | Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon Dots |
| title_sort | detection of ferric ions and catecholamine neurotransmitters via highly fluorescent heteroatom co doped carbon dots |
| topic | off-on fluorescence detector bi-sensor co-doped carbon dots improved quantum yield |
| url | https://www.mdpi.com/1424-8220/20/12/3470 |
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