Zanthoxylum bungeanum seed oil inhibits tumorigenesis of human melanoma A375 by regulating CDC25A/CyclinB1/CDK1 signaling pathways in vitro and in vivo

Zanthoxylum bungeanum seed oil inhibits tumorigenesis of human melanoma A375 by regulating CDC25A/CyclinB1/CDK1 signaling pathways in vitro and in vivo

Background:Zanthoxylum bungeanum seed oil (ZBSO) is extracted from the seeds of the traditional Chinese medicine Z. bungeanum Maxim, which has been shown to have anti-melanoma effects. However, the specific mechanisms are not illustrated adequately.Aims: To further investigate the mechanism by which...

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Bibliographic Details
Main Authors: Wanting Wang, Wenwen Pang, Suying Yan, Xiaoli Zheng, Qiurong Han, Yao Yao, Leixin Jin, Chunze Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Pharmacology
Subjects:
melanoma
Zanthoxylum bungeanum seed oil
cell cycle protein
CDC25A/CyclinB1/CDK1 pathway
gut microbes
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1165584/full

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