Long-Term Denervated Rat Schwann Cells Retain Their Capacity to Proliferate and to Myelinate Axons in vitro

Long-Term Denervated Rat Schwann Cells Retain Their Capacity to Proliferate and to Myelinate Axons in vitro

Functional recovery is poor after peripheral nerve injury and delayed surgical repair or when nerves must regenerate over long distances to reinnervate distant targets. A reduced capacity of Schwann cells (SCs) in chronically denervated distal nerve stumps to support and interact with regenerating a...

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Bibliographic Details
Main Authors: Tessa Gordon, Patrick Wood, Olawale A. R. Sulaiman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Schwann cells
nerve transection
myelination
SC proliferation
neurites
nerve injury
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00511/full

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