Joining Forces: The Combined Application of Therapeutic Viruses and Nanomaterials in Cancer Therapy
Cancer, on a global scale, presents a monumental challenge to our healthcare systems, posing a significant threat to human health. Despite the considerable progress we have made in the diagnosis and treatment of cancer, realizing precision cancer therapy, reducing side effects, and enhancing efficac...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/22/7679 |
| _version_ | 1797458180587913216 |
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| author | Hongyu Li Yunhuan Zhu Xin Wang Yilu Feng Yuncheng Qian Qiman Ma Xinyuan Li Yihan Chen Keda Chen |
| author_facet | Hongyu Li Yunhuan Zhu Xin Wang Yilu Feng Yuncheng Qian Qiman Ma Xinyuan Li Yihan Chen Keda Chen |
| author_sort | Hongyu Li |
| collection | DOAJ |
| description | Cancer, on a global scale, presents a monumental challenge to our healthcare systems, posing a significant threat to human health. Despite the considerable progress we have made in the diagnosis and treatment of cancer, realizing precision cancer therapy, reducing side effects, and enhancing efficacy remain daunting tasks. Fortunately, the emergence of therapeutic viruses and nanomaterials provides new possibilities for tackling these issues. Therapeutic viruses possess the ability to accurately locate and attack tumor cells, while nanomaterials serve as efficient drug carriers, delivering medication precisely to tumor tissues. The synergy of these two elements has led to a novel approach to cancer treatment—the combination of therapeutic viruses and nanomaterials. This advantageous combination has overcome the limitations associated with the side effects of oncolytic viruses and the insufficient tumoricidal capacity of nanomedicines, enabling the oncolytic viruses to more effectively breach the tumor’s immune barrier. It focuses on the lesion site and even allows for real-time monitoring of the distribution of therapeutic viruses and drug release, achieving a synergistic effect. This article comprehensively explores the application of therapeutic viruses and nanomaterials in tumor treatment, dissecting their working mechanisms, and integrating the latest scientific advancements to predict future development trends. This approach, which combines viral therapy with the application of nanomaterials, represents an innovative and more effective treatment strategy, offering new perspectives in the field of tumor therapy. |
| first_indexed | 2024-03-09T16:34:21Z |
| format | Article |
| id | doaj.art-7bf4836007b040bc8be6ccddb6c286fe |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T16:34:21Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-7bf4836007b040bc8be6ccddb6c286fe2023-11-24T14:58:41ZengMDPI AGMolecules1420-30492023-11-012822767910.3390/molecules28227679Joining Forces: The Combined Application of Therapeutic Viruses and Nanomaterials in Cancer TherapyHongyu Li0Yunhuan Zhu1Xin Wang2Yilu Feng3Yuncheng Qian4Qiman Ma5Xinyuan Li6Yihan Chen7Keda Chen8Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, ChinaShulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, ChinaCenter of Infectious Disease Research, School of Life Science, Westlake University, Hangzhou 310024, ChinaShulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, ChinaShulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, ChinaShulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, ChinaShulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, ChinaShulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, ChinaShulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, ChinaCancer, on a global scale, presents a monumental challenge to our healthcare systems, posing a significant threat to human health. Despite the considerable progress we have made in the diagnosis and treatment of cancer, realizing precision cancer therapy, reducing side effects, and enhancing efficacy remain daunting tasks. Fortunately, the emergence of therapeutic viruses and nanomaterials provides new possibilities for tackling these issues. Therapeutic viruses possess the ability to accurately locate and attack tumor cells, while nanomaterials serve as efficient drug carriers, delivering medication precisely to tumor tissues. The synergy of these two elements has led to a novel approach to cancer treatment—the combination of therapeutic viruses and nanomaterials. This advantageous combination has overcome the limitations associated with the side effects of oncolytic viruses and the insufficient tumoricidal capacity of nanomedicines, enabling the oncolytic viruses to more effectively breach the tumor’s immune barrier. It focuses on the lesion site and even allows for real-time monitoring of the distribution of therapeutic viruses and drug release, achieving a synergistic effect. This article comprehensively explores the application of therapeutic viruses and nanomaterials in tumor treatment, dissecting their working mechanisms, and integrating the latest scientific advancements to predict future development trends. This approach, which combines viral therapy with the application of nanomaterials, represents an innovative and more effective treatment strategy, offering new perspectives in the field of tumor therapy.https://www.mdpi.com/1420-3049/28/22/7679therapeutic virusesnanomaterialstumor treatmentdrug carrierscombined application |
| spellingShingle | Hongyu Li Yunhuan Zhu Xin Wang Yilu Feng Yuncheng Qian Qiman Ma Xinyuan Li Yihan Chen Keda Chen Joining Forces: The Combined Application of Therapeutic Viruses and Nanomaterials in Cancer Therapy Molecules therapeutic viruses nanomaterials tumor treatment drug carriers combined application |
| title | Joining Forces: The Combined Application of Therapeutic Viruses and Nanomaterials in Cancer Therapy |
| title_full | Joining Forces: The Combined Application of Therapeutic Viruses and Nanomaterials in Cancer Therapy |
| title_fullStr | Joining Forces: The Combined Application of Therapeutic Viruses and Nanomaterials in Cancer Therapy |
| title_full_unstemmed | Joining Forces: The Combined Application of Therapeutic Viruses and Nanomaterials in Cancer Therapy |
| title_short | Joining Forces: The Combined Application of Therapeutic Viruses and Nanomaterials in Cancer Therapy |
| title_sort | joining forces the combined application of therapeutic viruses and nanomaterials in cancer therapy |
| topic | therapeutic viruses nanomaterials tumor treatment drug carriers combined application |
| url | https://www.mdpi.com/1420-3049/28/22/7679 |
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