Structure of native chromatin fibres revealed by Cryo-ET in situ

Abstract The structure of chromatin plays pivotal roles in regulating gene transcription, DNA replication and repair, and chromosome segregation. This structure, however, remains elusive. Here, using cryo-FIB and cryo-ET, we delineate the 3D architecture of native chromatin fibres in intact interpha...

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Bibliographic Details
Main Authors: Zhen Hou, Frank Nightingale, Yanan Zhu, Craig MacGregor-Chatwin, Peijun Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42072-1