DNA methylation mediated RSPO2 to promote follicular development in mammals

DNA methylation mediated RSPO2 to promote follicular development in mammals

Abstract In female mammals, the proliferation, apoptosis, and estradiol-17β (E2) secretion of granulosa cells (GCs) have come to decide the fate of follicles. DNA methylation and RSPO2 gene of Wnt signaling pathway have been reported to involve in the survival of GCs and follicular development. Howe...

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Bibliographic Details
Main Authors:	Xiaofeng Zhou, Yingting He, Nian Li, Guofeng Bai, Xiangchun Pan, Zhe Zhang, Hao Zhang, Jiaqi Li, Xiaolong Yuan
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-06-01
Series:	Cell Death and Disease
Online Access:	https://doi.org/10.1038/s41419-021-03941-z

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