Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity
Two iPSC clones, NCCSi008-A and NCCSi008-B, were generated from a healthy male individual of Indian origin by reprogramming his CD4+ T cells with an integration free Sendai viral vector. The established iPSC clones showed high alkaline phosphatase (ALP) activity, expression of pluripotency markers,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-05-01
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| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506120300696 |
| _version_ | 1819012877717078016 |
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| author | Arun Vaidyanath Mohsina Khan Anjali Shiras |
| author_facet | Arun Vaidyanath Mohsina Khan Anjali Shiras |
| author_sort | Arun Vaidyanath |
| collection | DOAJ |
| description | Two iPSC clones, NCCSi008-A and NCCSi008-B, were generated from a healthy male individual of Indian origin by reprogramming his CD4+ T cells with an integration free Sendai viral vector. The established iPSC clones showed high alkaline phosphatase (ALP) activity, expression of pluripotency markers, a normal male karyotype consistent with the donor gender (46, XY) and has potential for multi-lineage differentiation. These iPSC lines of Indian origin would serve as valuable resources for disease modeling, drug development and screening. |
| first_indexed | 2024-12-21T01:51:02Z |
| format | Article |
| id | doaj.art-7bfd5c7b87a147268e762bee60bd46b5 |
| institution | Directory Open Access Journal |
| issn | 1873-5061 |
| language | English |
| last_indexed | 2024-12-21T01:51:02Z |
| publishDate | 2020-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Stem Cell Research |
| spelling | doaj.art-7bfd5c7b87a147268e762bee60bd46b52022-12-21T19:19:54ZengElsevierStem Cell Research1873-50612020-05-0145Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicityArun Vaidyanath0Mohsina Khan1Anjali Shiras2National Centre for Cell Science (NCCS), Ganeshkhind Road, Pune 411007 IndiaNational Centre for Cell Science (NCCS), Ganeshkhind Road, Pune 411007 IndiaCorresponding author.; National Centre for Cell Science (NCCS), Ganeshkhind Road, Pune 411007 IndiaTwo iPSC clones, NCCSi008-A and NCCSi008-B, were generated from a healthy male individual of Indian origin by reprogramming his CD4+ T cells with an integration free Sendai viral vector. The established iPSC clones showed high alkaline phosphatase (ALP) activity, expression of pluripotency markers, a normal male karyotype consistent with the donor gender (46, XY) and has potential for multi-lineage differentiation. These iPSC lines of Indian origin would serve as valuable resources for disease modeling, drug development and screening.http://www.sciencedirect.com/science/article/pii/S1873506120300696 |
| spellingShingle | Arun Vaidyanath Mohsina Khan Anjali Shiras Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity Stem Cell Research |
| title | Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity |
| title_full | Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity |
| title_fullStr | Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity |
| title_full_unstemmed | Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity |
| title_short | Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity |
| title_sort | generation of two control ipsc clones nccsi008 a and nccsi008 b from an individual of indian ethnicity |
| url | http://www.sciencedirect.com/science/article/pii/S1873506120300696 |
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